Evidence map›Paper›PMID 22251008›Full record

ReviewInternational reviews of immunology2012

Alternative medicines as emerging therapies for inflammatory bowel diseases.

Udai P Singh, Narendra P Singh, Brandon Busbee, H Guan, Balwan Singh, Robert L Price, Dennis D Taub, Manoj K Mishra, Mitzi Nagarkatti, Prakash S Nagarkatti

Abstract readReview
In one paragraph

Review in International reviews of immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Emerging role of protein modification in inflammatory bowel disease.Journal of Zhejiang University. Science. B · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Udai P SinghDepartment of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina 29208, USA. Udai.singh@uscmed.sc.edu
Narendra P Singh
Brandon Busbee
H Guan
Balwan Singh
Robert L Price
Dennis D Taub
Manoj K Mishra
Mitzi Nagarkatti
Prakash S Nagarkatti
University of South Carolina · USAlabama State University · USEmory University · US

Funding

Use of Resveratrol to treat experimental multiple sclerosisP01AT003961 · NCCIH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NAGARKATTI, PRAKASH S · 2007 to 2018
$14.2M
Novel Interactions Between the Immune and Neuroendocrine SystemsZIAAG000758 · NIA · NATIONAL INSTITUTE ON AGING · PI SEN, RANJAN · 2009 to 2013
$4.4M
Intramural NIH HHSNCCIH NIH HHS P01 AT003961NCCIH NIH HHS P01AT003961
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) can be divided into two major categories, ulcerative colitis (UC) and Crohn disease (CD). While the main cause(s) of IBD remain unknown, a number of interventional and preventive strategies have been proposed for use against CD and UC. Many reports have focused on the use of alternative natural medicines as potential therapeutic interventions in IBD patients with minimal side effects. While the use of alternative medicines may be effective in IBD patients that are refractory to corticosteroids or thiopurins, alternative treatment strategies are limited and require extensive clinical testing before being optimized for use in patients.

Indexed as

PhytotherapyAdrenal Cortex HormonesAnimalsClinical Trials as TopicComplementary TherapiesHumansInflammatory Bowel DiseasesPlantsResveratrolRutinStilbenesAdrenal Cortex HormonesResveratrolRutinStilbenes

Identifiers

PMID22251008
PMCPMC4138959
OpenAlexW2120220917

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.