Evidence map›Paper›PMID 22251005›Full record

ReviewInternational reviews of immunology2012

Perspective for prophylaxis and treatment of cervical cancer: an immunological approach.

Marjorie Jenkins, Maurizio Chiriva-Internati, Leonardo Mirandola, Catherine Tonroy, Sean S Tedjarati, Nicole Davis, Nicholas D'Cunha, Lukman Tijani, Fred Hardwick, Diane Nguyen and 2 more

Abstract readReview
In one paragraph

Review in International reviews of immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Marjorie JenkinsDivision of Hematology & Oncology, Texas Tech University Health Sciences Center and Southwest Cancer Treatment and Research Center, Lubbock, Texas 79430, USA.
Maurizio Chiriva-Internati
Leonardo Mirandola
Catherine Tonroy
Sean S Tedjarati
Nicole Davis
Nicholas D'Cunha
Lukman Tijani
Fred Hardwick
Diane Nguyen
W Martin Kast
Everardo Cobos
Texas Tech University Health Sciences Center · USTexas Tech University · USCancer Center of Hawaii · US

Funding

VLP VACCINES AGAINST HPV INDUCED TUMORSR01CA074397 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAST, WIJBE MARTIN · 1997 to 2020
$5.5M
Exploration of novel pan-HPV treatments to block development of AIDS-associated cRC2CA148298 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAST, WIJBE MARTIN · 2009 to 2010
$1.0M
NCI NIH HHS R01 CA074397NCI NIH HHS R01 CA74397-11NCI NIH HHS RC2 CA148298NCI NIH HHS RC2 CA148298-01
6 · The paper itself

Abstract

As the second most common cause of cancer-related death in women, human papilloma virus (HPV) vaccines have been a major step in decreasing the morbidity and mortality associated with cervical cancer. An estimated 490,000 women are diagnosed with cervical cancer each year. Increasing knowledge of the HPV role in the etiology of cervical cancer has led to the development and introduction of HPV-based vaccines for active immunotherapy of cervical cancer. Immunotherapies directed at preventing HPV-persistent infections. These vaccines are already accessible for prophylaxis and in the near future, they will be available for the treatment of preexisting HPV-related neoplastic lesions.

Indexed as

Immunotherapy, ActiveAlphapapillomavirusAnimalsCarcinomaCell Transformation, NeoplasticCell Transformation, ViralFemaleHumansPapillomavirus InfectionsPapillomavirus VaccinesSexually Transmitted Diseases, ViralUterine Cervical NeoplasmsPapillomavirus Vaccines

Identifiers

PMID22251005
PMCPMC4164215
OpenAlexW1966900258

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.