ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2012
The effect of cost on adherence to prescription medications in Canada.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
109 citing papers in PubMed, 1 synthesis or guideline pooled it, 236 citations in OpenAlex.
- Cost-related medication nonadherence in Canada: a systematic review of prevalence, predictors, and clinical impact.Systematic reviews · 2021Pooled it
- Trial
- Exploring the experiences of people in Ontario, Canada who have trouble affording medicines: a qualitative concept mapping study.BMJ open · 2019Trial
- Trial
- Disparities in cost-related prescription nonadherence between Black and White adults in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- Antiretroviral utilization and adherence before vs. after expansion of a provincial drug insurance policy.AIDS (London, England) · 2026Article
- Providers' Perspectives and Experiences with Cost-Related Nonadherence to Medications: A Thematic Analysis.Risk management and healthcare policy · 2026Article
- Universal Pharmacare and Contraceptive Dispensations Among Youth.JAMA pediatrics · 2025Article
- Effect of universal no-cost coverage on use of long-acting reversible contraception and all prescription contraception: population based, controlled, interrupted time series analysis.BMJ (Clinical research ed.) · 2025Article
- Predictors of cost-related medication nonadherence in Canada: a repeated cross-sectional analysis of the Canadian Community Health Survey.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024Article
- Income-Related Inequities in Primary and Specialist Care Among First Nations Peoples Living Off-Reserve in Canada.Journal of racial and ethnic health disparities · 2024Article
- A retrospective analysis of e-prescriptions for non-communicable diseases on a telehealth platform in Malaysia.BMC health services research · 2024Observational
- Longitudinal study of the impact of the COVID-19 pandemic on diet and physical activity among Latinos of Mexican ancestry.Journal of translational medicine · 2024Article
- Clinical factors associated with patterns of endocrine therapy adherence in premenopausal breast cancer patients.Breast cancer research : BCR · 2024Article
- The Intersectional Impact of Cost-Related Non-Adherence and Depression: A Cross-Sectional Analysis of the Canadian Community Health Survey by Sex, Race, and Indigeneity.Community mental health journal · 2024Article
- An Optional Delinked Reward System: Making Pharmaceutical Innovation Work for Everyone.Applied health economics and health policy · 2024Article
- GLP-1 Agonism for Kidney Transplant Recipients: A Narrative Review of Current Evidence and Future Directions Across the Research Spectrum.Canadian journal of kidney health and disease · 2024Review
- Underprescription of Fibrate Among Patients With Diabetic Retinopathy in Perak, Malaysia.Cureus · 2024Article
- Barriers to adherence to antiretroviral therapy: identifying priority areas for people with HIV and healthcare professionals.International journal of STD & AIDS · 2023Article
- Prevalence and predictors of primary nonadherence to medications prescribed in primary care.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Article
49 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundMany patients do not adhere to treatment because they cannot afford their prescription medications, putting them at increased risk of adverse health outcomes. We determined the prevalence of cost-related nonadherence and investigated its associated characteristics, including whether a person has drug insurance.
methodsUsing data from the 2007 Canada Community Health Survey, we analyzed the responses of 5732 people who answered questions about cost-related nonadherence to treatment. We determined the national prevalence of cost-related nonadherence and used logistic regression to evaluate the association between cost-related nonadherence and a series of demographic and socioeconomic variables, including province of residence, age, sex, household income, health status and having drug insurance.
resultsCost-related nonadherence was reported by 9.6% (95% confidence interval [CI] 8.5%-10.6%) of Canadians who had received a prescription in the past year. In our adjusted model, we found that people in poor health (odds ratio [OR] 2.64, 95% CI 1.77-3.94), those with lower income (OR 3.29, 95% CI 2.03-5.33), those without drug insurance (OR 4.52, 95% CI 3.29-6.20) and those who live in British Columbia (OR 2.56, 95% CI 1.49-4.42) were more likely to report cost-related nonadherence. Predicted rates of cost-related nonadherence ranged from 3.6% (95% CI 2.4-4.5) among people with insurance and high household incomes to 35.6% (95% CI 26.1%-44.9%) among people with no insurance and low household incomes.
interpretationAbout 1 in 10 Canadians who receive a prescription report cost-related nonadherence. The variability in insurance coverage for prescription medications appears to be a key reason behind this phenomenon.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.