Evidence map›Paper›PMID 22249913›Full record

ReviewCerebellum (London, England)2012

Parasagittal zones in the cerebellar cortex differ in excitability, information processing, and synaptic plasticity.

Timothy J Ebner, Xinming Wang, Wangcai Gao, Samuel W Cramer, Gang Chen

Open access · greenAbstract readReview
In one paragraph

Review in Cerebellum (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. TRPC3-dependent synaptic transmission in central mammalian neurons.Journal of molecular medicine (Berlin, Germany) · 2015
    Review
  13. Article
  14. Cerebellar zonal patterning relies on Purkinje cell neurotransmission.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
  15. Article
  16. Review
  17. The neuronal code(s) of the cerebellum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Review
  18. Article
  19. Linking oscillations in cerebellar circuits.Frontiers in neural circuits · 2013
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Timothy J EbnerDepartment of Neuroscience, University of Minnesota, 2001 Sixth Street SE, Minneapolis, MN 55455, USA. ebner001@umn.edu
Xinming Wang
Wangcai Gao
Samuel W Cramer
Gang Chen
University of Minnesota · US

Funding

Temporal/spatial RNA Expression Effects in DM1 and DM2P01NS058901 · NINDS · UNIVERSITY OF MINNESOTA · PI RANUM, LAURA P.W · 2008 to 2017
$12.3M
PREDOCTORAL TRAINING OF NEUROSCIENTISTST32GM008471 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI EBNER, TIMOTHY J · 1993 to 2017
$4.9M
ROLE OF THE CEREBELLUM IN VISUALLY GUIDED ARM MOVEMENTSR01NS018338 · NINDS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI EBNER, TIMOTHY J · 1985 to 2020
$4.7M
NINDS Center Core at the University of MinnesotaP30NS062158 · NINDS · UNIVERSITY OF MINNESOTA · PI ORR, HARRY T. · 2011 to 2015
$3.5M
Optical Imaging of Cerebellar Plasticity In VivoR01NS048944 · NINDS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI EBNER, TIMOTHY J · 2005 to 2009
$1.6M
NIGMS NIH HHS T32 GM008471NINDS NIH HHS NS048944NINDS NIH HHS NS062158NINDS NIH HHS NS18338NINDS NIH HHS P01 NS058901NINDS NIH HHS P30 NS062158NINDS NIH HHS R01 NS018338NINDS NIH HHS R01 NS048944
6 · The paper itself

Abstract

At the molecular and circuitry levels, the cerebellum exhibits a striking parasagittal zonation as exemplified by the spatial distribution of molecules expressed on Purkinje cells and the topography of the afferent and efferent projections. The physiology and function of the zonation is less clear. Activity-dependent optical imaging has proven a useful tool to examine the physiological properties of the parasagittal zonation in the intact animal. Recent findings show that zebrin II-positive and zebrin II-negative zones differ markedly in their responses to parallel fiber inputs. These findings suggest that cerebellar cortical excitability, information processing, and synaptic plasticity depend on the intrinsic properties of different parasagittal zones.

Indexed as

AnimalsCerebellar CortexFlavoproteinsHumansMental ProcessesNerve Tissue ProteinsNeuronal PlasticityPurkinje CellsReceptors, Metabotropic GlutamateSignal TransductionSynapsesFlavoproteinsmetabotropic glutamate receptor type 1Nerve Tissue ProteinsReceptors, Metabotropic Glutamatezebrin II

Identifiers

PMID22249913
PMCPMC3856581
OpenAlexW2135073189

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.