Evidence map›Paper›PMID 22249519›Full record

ReviewNature reviews. Endocrinology2012

Nonpharmacological interventions for the prevention of type 2 diabetes mellitus.

Peter E Schwarz, Colin J Greaves, Jaana Lindström, Thomas Yates, Melanie J Davies

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 122 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Peter E SchwarzDepartment for Prevention and Care of Diabetes, Medical Clinic III, University Clinic Carl Gustav Carus at the Technical University Dresden, Fetscherstrasse 74, D-01307 Dresden, Germany. peter.schwarz@uniklinikum-dresden.de
Colin J Greaves
Jaana Lindström
Thomas Yates
Melanie J Davies
University of Leicester · GBFinnish Institute for Health and Welfare · FITU Dresden · DEUniversity of Exeter · GB

Funding

Department of Health PDA/02/06/031Department of Health RP-DG-1210-10183Department of Health RP-PG-0606-1272
6 · The paper itself

Abstract

During the past decade, improved understanding of the pathophysiological mechanisms of diabetes development has resulted in advances in therapeutic concepts, but has also supported the potential for diabetes prevention through nonpharmacological means. At the beginning of the century, we experienced a shift in paradigm, as landmark studies have shown that diabetes mellitus is preventable with lifestyle intervention; moderate changes in diet and physical activity produce a substantial and sustained reduction in the incidence of type 2 diabetes mellitus (T2DM) for individuals with impaired glucose tolerance. This evidence must now be translated into clinical and public-health practice, but translational studies have varied in their ability to replicate the results of clinical trials. This variation reflects a number of challenging barriers for diabetes prevention in real-world clinical practice, which makes it necessary to focus on identifying efficient intervention methods and delivery mechanisms. Research is now focusing on these mechanisms, as well as on developing efficient screening and risk-identification strategies and realistic scenarios for public-health policy to implement diabetes prevention programs. In this Review, we will discuss these mechanisms and will consider the implications of diabetes prevention for public-health strategy and policy.

Indexed as

DietMotor ActivityDiabetes Mellitus, Type 2HumansLife StylePublic HealthRisk Factors

Identifiers

PMID22249519
OpenAlexW2020776251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.