ArticleBehavioural brain research2012
Sensory feedback modulates quipazine-induced stepping behavior in the newborn rat.
Article in Behavioural brain research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Development of Locomotor-Related Movements in Early Infancy.Frontiers in cellular neuroscience · 2020Article
- Locomotion and posture development in immature male and female rats (Rattus norvegicus): Comparison of sensory-enriched versus sensory-deprived testing environments.Journal of comparative psychology (Washington, D.C. : 1983) · 2019Article
- Stimulation of 5-HT2A receptors recovers sensory responsiveness in acute spinal neonatal rats.Behavioral neuroscience · 2017Article
- Serotonergic activation of locomotor behavior and posture in one-day old rats.Behavioural brain research · 2016Article
- Posture effects on spontaneous limb movements, alternated stepping, and the leg extension response in neonatal rats.Physiology & behavior · 2016Article
- Developmental plasticity of coordinated action patterns in the perinatal rat.Developmental psychobiology · 2015Review
- Spinal mediation of motor learning and memory in the rat fetus.Developmental psychobiology · 2015Article
- Range of motion (ROM) restriction influences quipazine-induced stepping behavior in postnatal day one and day ten rats.Behavioural brain research · 2014Article
- Prematurely delivered rats show improved motor coordination during sensory-evoked motor responses compared to age-matched controls.Physiology & behavior · 2014Article
- Serotonergic modulation of post-synaptic inhibition and locomotor alternating pattern in the spinal cord.Frontiers in neural circuits · 2014Review
- Inter- and intralimb adaptations to a sensory perturbation during activation of the serotonin system after a low spinal cord transection in neonatal rats.Frontiers in neural circuits · 2014Article
- A neonatal mouse spinal cord injury model for assessing post-injury adaptive plasticity and human stem cell integration.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Research has shown that sensory feedback modulates locomotor behavior in intact as well as spinal adult animals. Here we examined if locomotor activity ("stepping") in newborn rats is influenced by cutaneous and proprioceptive feedback. One-day-old rats were treated with the serotonergic receptor agonist quipazine (3.0mg/kg) to induce air-stepping behavior or with saline (vehicle control). During stepping, a substrate/floor (elastic, stiff, or none) was placed beneath their limbs so that the feet could make plantar surface contact with a substrate. Pups treated with quipazine showed significantly more alternated fore- and hindlimb steps and plantar paw contact with the substrate, compared to pups treated with saline. Pups also made proportionately less contact with the stiff substrate versus the elastic substrate during stepping. Different types of movements made on the substrate (paw pushes, taps, swipes, and stances) were also characterized. These results indicate that sensory feedback modulates locomotor mechanisms and behavior in perinatal rats.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.