Evidence map›Paper›PMID 22248713›Full record

ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2012

National Cancer Institute, National Heart, Lung and Blood Institute/Pediatric Blood and Marrow Transplantation Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: the need for pediatric-specific long-term follow-up guidelines.

Michael A Pulsipher, Roderick Skinner, George B McDonald, Sangeeta Hingorani, Saro H Armenian, Kenneth R Cooke, Clarisa Gracia, Anna Petryk, Smita Bhatia, Nancy Bunin and 6 more

Registry-linked trialOpen access · bronzeAbstract readConsensus Development Conference, NIH
In one paragraph

Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03072849 (Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03072849 completednot on this mapstarted 2015, after this paper: background citation

Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation

TypeobservationalSponsorAnn & Robert H Lurie Children's Hospital of ChicagoRan2015 to 2020Enrolled23ConditionsBronchiolitis Obliterans SyndromeArmsPulmonary function testing, FAM Therapy
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Guideline
  2. Metabolic Syndrome and Cardiovascular Disease after Hematopoietic Cell Transplantation: Screening and Preventive Practice Recommendations from the CIBMTR and EBMT.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2016
    Guideline
  3. Trial
  4. Trial
  5. Bone mineral density in children with fanconi anemia after hematopoietic cell transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2015
    Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Late Effects Following Hematopoietic Stem Cell Transplantation Among Childhood Transplant Survivors with Fanconi AnemiaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 13 institutions in 3 countries.

Michael A PulsipherPrimary Children's Medical Center, University of Utah School of Medicine/Huntsman Cancer Institute, Division of Hematology/BMT, Salt Lake City, Utah 84132, USA. michael.pulsipher@hsc.utah.edu
Roderick Skinner
George B McDonald
Sangeeta Hingorani
Saro H Armenian
Kenneth R Cooke
Clarisa Gracia
Anna Petryk
Smita Bhatia
Nancy Bunin
Michael L Nieder
Christopher C Dvorak
Lillian Sung
Jean E Sanders
Joanne Kurtzberg
K Scott Baker
Fred Hutch Cancer Center · USCity of Hope · USChildren's Hospital of Philadelphia · USDuke University Hospital · USGreat North Children's Hospital · GBHospital for Sick Children · CAJohns Hopkins All Children's Hospital · USPrimary Children's Hospital · USRainbow Babies & Children's Hospital · USUCSF Benioff Children's Hospital · USUniversity of Minnesota Children's Hospital · USUniversity of Pennsylvania · USUniversity of Washington · US

Funding

Metabolic Syndrome Following Transplant for LeukemiaR01CA112530 · NCI · UNIVERSITY OF MINNESOTA · PI BAKER, KEVIN S · 2006 to 2010
$2.2M
Pediatric Blood and Marrow Transplant ConsortiumU01HL069254 · NHLBI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI PULSIPHER, MICHAEL A · 2001 to 2010
$2.0M
Blood and Marrow Transplant Clinical Trials NetworkU10HL069254 · NHLBI · UNIVERSITY OF UTAH · PI PULSIPHER, MICHAEL A · 2011 to 2016
$839k
Late Effects after Pediatric HSCT: State of the Science, Future DirectionsR13CA159788 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI BAKER, KEVIN S, PULSIPHER, MICHAEL A · 2011 to 2011
$13k
NCI NIH HHS 1R13CA159788-01NCI NIH HHS R01 CA112530NCI NIH HHS R13 CA159788NHLBI NIH HHS U01 HL069254NHLBI NIH HHS U01HL069254NHLBI NIH HHS U10 HL069254
6 · The paper itself

Abstract

Existing standards for screening and management of late effects occurring in children who have undergone hematopoietic cell transplantation (HCT) include recommendations from pediatric cancer networks and consensus guidelines from adult-oriented transplantation societies applicable to all HCT recipients. Although these approaches have significant merit, they are not pediatric HCT-focused, and they do not address post-HCT challenges faced by children with complex nonmalignant disorders. In this article we discuss the strengths and weaknesses of current published recommendations and conclude that pediatric-specific guidelines for post-HCT screening and management would be beneficial to the long-term health of these patients and would promote late effects research in this field. Our panel of late effects experts also provides recommendations for follow-up and therapy of selected post-HCT organ and endocrine complications in pediatric patients.

Indexed as

ChildFollow-Up StudiesHematopoietic Stem Cell TransplantationHumansNational Cancer Institute (U.S.)PediatricsPractice Guidelines as TopicUnited States

Identifiers

PMID22248713
PMCPMC3281504
OpenAlexW2150733695

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.