Evidence map›Paper›PMID 22248595›Full record

ArticleGastrointestinal endoscopy2012

Validation of the Prague C & M criteria for the endoscopic grading of Barrett's esophagus by gastroenterology trainees: a multicenter study.

Babac Vahabzadeh, Anil B Seetharam, Michael B Cook, Sachin Wani, Amit Rastogi, Ajay Bansal, Dayna S Early, Prateek Sharma

Abstract readMulticenter StudyValidation Study
In one paragraph

Article in Gastrointestinal endoscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Quality indicators for upper GI endoscopy.Gastrointestinal endoscopy · 2025
    Guideline
  3. Guideline
  4. Advances in the Diagnosis of Barrett's Esophagus.Diagnostics (Basel, Switzerland) · 2026
    Review
  5. Quality Indicators for Upper GI Endoscopy.The American journal of gastroenterology · 2025
    Article
  6. Functional Endoscopy.Digestion · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Endoscopic management of esophageal cancer.World journal of gastrointestinal oncology · 2019
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Babac VahabzadehVeterans Affairs Medical Center, Kansas City, Missouri 64128-2295, USA.
Anil B Seetharam
Michael B Cook
Sachin Wani
Amit Rastogi
Ajay Bansal
Dayna S Early
Prateek Sharma

Funding

Barretts EsophagusZIACP010220 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ABNET, CHRISTIAN · 2011 to 2025
$4.5M
Intramural VA VA999999
6 · The paper itself

Abstract

backgroundThe Prague C & M criteria, developed for the endoscopic grading of Barrett's esophagus (BE), (C = circumferential length, M = maximal length) were previously validated among a panel of 29 expert endoscopists with a special interest in BE. Its performance among gastroenterology trainees is unknown.

objectiveTo test interobserver agreement among gastroenterology trainees for the Prague C & M criteria, identification of the gastroesophageal junction (GEJ) and the diaphragmatic hiatus.

designA prospective study.

settingTwo tertiary referral centers. PATIENTS AND

interventionsStandardized endoscopic videos were used. MAIN OUTCOME MEASUREMENTS: Interobserver agreement.

resultsEighteen high-quality videos (normal esophagus, short and long lengths of BE, equally distributed) were independently evaluated by 18 gastroenterology trainees (year 1, n = 5; year 2, n = 6; year 3, n = 7) after administration of a formal teaching module by an expert endoscopist. Overall intraclass correlation coefficients for assessment of the C and M extent of the endoscopic BE segment above the GEJ were 0.94 (95% CI, 0.89-0.98) and 0.96 (95% CI, 0.94-0.98), respectively. The overall intraclass correlation coefficients for GEJ and diaphragmatic hiatus location recognition were 0.92 (0.86-0.96) and 0.90 (0.82-0.95), respectively. The year of training did not affect interobserver agreement. LIMITATIONS: The use of videos for endoscopic evaluation.

conclusionAfter standardized teaching, the Prague C & M criteria have high overall validity among gastroenterology trainees irrespective of the level of training for endoscopic evaluation of visualized BE lengths as well as key endoscopic landmarks.

Indexed as

Barrett EsophagusConfidence IntervalsEsophagogastric JunctionEsophagoscopyGastroenterologyHumansObserver VariationProspective StudiesReproducibility of ResultsVideo Recording

Identifiers

PMID22248595
PMCPMC4547779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.