Evidence map›Paper›PMID 22248350›Full record

ArticleHuman gene therapy2012

Gene therapy for Fanconi anemia: one step closer to the clinic.

Jakub Tolar, Pamela S Becker, D Wade Clapp, Helmut Hanenberg, Cristina Díaz de Heredia, Hans-Peter Kiem, Susana Navarro, Pankaj Qasba, Paula Rio, Manfred Schmidt and 4 more

Abstract readConference Proceedings
In one paragraph

Article in Human gene therapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Multifaceted Fanconi Anemia Signaling.Trends in genetics : TIG · 2018
    Review
  4. Therapeutic gene editing in CD34EMBO molecular medicine · 2017
    Article
  5. Article
  6. Article
  7. Emerging cellular and gene therapies for congenital anemias.American journal of medical genetics. Part C, Seminars in medical genetics · 2016
    Review
  8. Stem cell-based therapies for HIV/AIDS.Advanced drug delivery reviews · 2016
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jakub TolarDivision of Blood and Marrow Transplantation, University of Minnesota , Minneapolis, MN 55455, USA. tolar003@umn.edu
Pamela S Becker
D Wade Clapp
Helmut Hanenberg
Cristina Díaz de Heredia
Hans-Peter Kiem
Susana Navarro
Pankaj Qasba
Paula Rio
Manfred Schmidt
Julián Sevilla
Els Verhoeyen
Adrian J Thrasher
Juan Bueren

Funding

Genetic Therapy for Fanconi AnemiaR01CA155294 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI CLAPP, DAVID W, HANENBERG, HELMUT · 2011 to 2015
$1.6M
NCI NIH HHS R01 CA155294NHLBI NIH HHS R01HL84645Wellcome Trust 090233
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsClinical Trials as TopicDNA DamageFanconi AnemiaFanconi Anemia Complementation Group A ProteinGenetic TherapyHumansFANCA protein, humanFanconi Anemia Complementation Group A Protein

Identifiers

PMID22248350
PMCPMC3277737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.