ArticleJournal of medical case reports2012
Ovarian germ cell tumors with rhabdomyosarcomatous components and later development of growing teratoma syndrome: a case report.
Article in Journal of medical case reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Spinal Metastases in Non-Seminomatous Germ Cell Testicular Tumors: Prognosis and Integrated Therapeutic Approaches-A Systematic Review with an Institutional Case Illustration.Current oncology (Toronto, Ont.) · 2024Pooled it
- Ovarian Rhabdomyosarcoma in Children.Cureus · 2025Article
- A case series and literature review on 98 pediatric patients of germ cell tumor developing growing teratoma syndrome.Cancer medicine · 2023Review
- Pediatric growing teratoma syndrome of the ovary: A case report and review of the literature.Medicine · 2020Review
- Managing growing teratoma syndrome: new insights and clinical applications.Future science OA · 2019Article
- Peripheral Primitive Neuroectodermal Tumor of the Ovary: The Report of Two Rare Cases.Iranian journal of pathology · 2018Article
- Pediatric Ovarian Growing Teratoma Syndrome.Case reports in surgery · 2017Article
- Growing Teratoma Syndrome Secondary to Ovarian Giant Immature Teratoma in an Adolescent Girl: A Case Report and Literature Review.Medicine · 2016Article
- Central primary primitive neuroectodermal tumor (cPNET) arising from an ovarian mature cystic teratoma in pregnancy: A case report and review of medical literature.Gynecologic oncology case reports · 2013Article
- Ovarian Sarcoma a Diagnostic Dilemma- A Case Report.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDevelopment of a sarcomatous component in a germ cell tumor is an uncommon phenomenon. Most cases reported have a grim prognosis. Growing teratoma syndrome is also an uncommon phenomenon and occurs in approximately 2% to 7% of non seminomatous germ cell tumors and should be treated surgically. CASE PRESENTATION: We report the case of a 12-year-old Asian girl with an ovarian mixed germ cell tumor containing a rhabdomyosarcomatous component. She was treated with a germ cell tumor chemotherapy regimen and rhabdomyosarcoma-specific chemotherapy. Towards the end of her treatment, she developed a retroperitoneal mass that was increasing in size. It was completely resected, revealing a mature teratoma, consistent with growing teratoma syndrome. She is still in complete remission approximately three years after presentation.
conclusionThe presence of rhabdomyosarcoma in a germ cell tumor should be treated by a combined chemotherapy regimen (for germ cell tumor and rhabdomyosarcoma). In addition, development of a mass during or after therapy with normal serum markers should raise the possibility of growing teratoma syndrome that should be treated surgically.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.