ArticleApplied and environmental microbiology2012
Marked genomic diversity of norovirus genogroup I strains in a waterborne outbreak.
Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 66 citations in OpenAlex.
- Diverse genotypes of norovirus genogroup I and II contamination in environmental water in Thailand during the COVID-19 outbreak from 2020 to 2022.Virologica Sinica · 2024Article
- Population genomics of diarrheagenic Escherichia coli uncovers high connectivity between urban and rural communities in Ecuador.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2023Article
- Multiple Novel Human Norovirus Recombinants Identified in Wastewater in Pretoria, South Africa by Next-Generation Sequencing.Viruses · 2022Article
- A Bibliometric Analysis of the Literature on Norovirus Disease from 1991-2021.International journal of environmental research and public health · 2022Article
- Comparison of Skimmed Milk and Lanthanum Flocculation for Concentration of Pathogenic Viruses in Water.Food and environmental virology · 2021Article
- Risk factors for norovirus infection in healthcare workers during nosocomial outbreaks: a cross-sectional study.Antimicrobial resistance and infection control · 2021Article
- Understanding Pediatric Norovirus Epidemiology: A Decade of Study among Ghanaian Children.Viruses · 2020Article
- Secretor Status is Associated with Susceptibility to Disease in a Large GII.6 Norovirus Foodborne Outbreak.Food and environmental virology · 2020Article
- Norovirus Detection at Oualidia Lagoon, a Moroccan Shellfish Harvesting Area, by Reverse Transcription PCR Analysis.Food and environmental virology · 2019Article
- Norovirus waterborne outbreak in Chalkidiki, Greece, 2015: detection of GI.P2_GI.2 and GII.P16_GII.13 unusual strains.Epidemiology and infection · 2019Article
- Waterborne outbreak of gastroenteritis on the KwaZulu-Natal Coast, South Africa, December 2016/January 2017.Epidemiology and infection · 2018Article
- Improved Detection of Norovirus and Hepatitis A Virus in Surface Water by Applying Pre-PCR Processing.Food and environmental virology · 2017Article
- One-year Surveillance of Human Enteric Viruses in Raw and Treated Wastewaters, Downstream River Waters, and Drinking Waters.Food and environmental virology · 2017Article
- An Outbreak of Norovirus Infections Among Lunch Customers at a Restaurant, Tampere, Finland, 2015.Food and environmental virology · 2016Article
- An Improved One-Step Real-Time Reverse Transcription-PCR Assay for Detection of Norovirus.Journal of clinical microbiology · 2016Article
- Environmental Surveillance of Genogroup I and II Noroviruses in Shandong Province, China in 2013.Scientific reports · 2015Article
- Lesser-known or hidden reservoirs of infection and implications for adequate prevention strategies: Where to look and what to look for.GMS hygiene and infection control · 2015Review
- Norovirus GII.17 Predominates in Selected Surface Water Sources in Kenya.Food and environmental virology · 2014Article
- UVC Inactivation of dsDNA and ssRNA Viruses in Water: UV Fluences and a qPCR-Based Approach to Evaluate Decay on Viral Infectivity.Food and environmental virology · 2014Article
- Detection of pathogenic viruses in sewage provided early warnings of hepatitis A virus and norovirus outbreaks.Applied and environmental microbiology · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marked norovirus (NoV) diversity was detected in patient samples from a large community outbreak of gastroenteritis with waterborne epidemiology affecting approximately 2,400 people. NoV was detected in 33 of 50 patient samples examined by group-specific real-time reverse transcription-PCR. NoV genotype I (GI) strains predominated in 31 patients, with mixed GI infections occurring in 5 of these patients. Sequence analysis of RNA-dependent polymerase-N/S capsid-coding regions (∼900 nucleotides in length) confirmed the dominance of the GI strains (n = 36). Strains of NoV GI.4 (n = 21) and GI.7 (n = 9) were identified, but six strains required full capsid amino acid analyses (530 to 550 amino acids) based on control sequencing of cloned amplicons before the virus genotype could be determined. Three strains were assigned to a new NoV GI genotype, proposed as GI.9, based on capsid amino acid analyses showing 26% dissimilarity from the established genotypes GI.1 to GI.8. Three other strains grouped in a sub-branch of GI.3 with 13 to 15% amino acid dissimilarity to GI.3 GenBank reference strains. Phylogenetic analysis (2.1 kb) of 10 representative strains confirmed these genotype clusters. Strains of NoV GII.4 (n = 1), NoV GII.6 (n = 2), sapovirus GII.2 (n = 1), rotavirus (n = 3), adenovirus (n = 1), and Campylobacter spp. (n = 2) were detected as single infections or as mixtures with NoV GI. Marked NoV GI diversity detected in patients was consistent with epidemiologic evidence of waterborne NoV infections, suggesting human fecal contamination of the water supply. Recognition of NoV diversity in a cluster of patients provided a useful warning marker of waterborne contamination in the Lilla Edet outbreak.
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