ArticleThe Journal of infectious diseases2012
CD4+ cell count and HIV load as predictors of size of anal warts over time in HIV-infected women.
Article in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The trial behind it
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Who cites it
5 citing papers in PubMed.
- Human papillomavirus-related oral lesions in people with HIV: A 20-year multinational cohort analysis.Journal of dental sciences · 2026Article
- CD4 Trajectory Models and Onset of Non-AIDS-Defining Anal Genital Warts, Precancer, and Cancer in People Living With HIV Infection-1.Sexually transmitted diseases · 2020Article
- Comparison of Plasma Zinc Levels Among HIV+ and HIV- Subjects Infected with Condyloma AcuminataAsian Pacific journal of cancer prevention : APJCP · 2019Article
- Clinical implications of the cervical Papanicolaou test results in the management of anal warts in HIV-infected women.PloS one · 2013Article
- Association between smoking and size of anal warts in HIV-infected women.International journal of STD & AIDS · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundLittle is known about the associations between CD4(+) cell counts, human immunodeficiency virus (HIV) load, and human papillomavirus "low-risk" types in noncancerous clinical outcomes. This study examined whether CD4(+) count and HIV load predict the size of the largest anal warts in 976 HIV-infected women in an ongoing cohort.
methodsA linear mixed model was used to determine the association between size of anal wart and CD4(+) count and HIV load.
resultsThe incidence of anal warts was 4.15 cases per 100 person-years (95% confidence interval [CI], 3.83-4.77) and 1.30 cases per 100 person-years (95% CI, 1.00-1.58) in HIV-infected and HIV-uninfected women, respectively. There appeared to be an inverse association between size of the largest anal warts and CD4(+) count at baseline; however, this was not statistically significant. There was no association between size of the largest anal warts and CD4(+) count or HIV load over time.
conclusionsThere was no evidence for an association between size of the largest anal warts and CD4(+) count or HIV load over time. Further exploration on the role of immune response on the development of anal warts is warranted in a larger study.
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