Evidence map›Paper›PMID 22246051›Full record

ReviewProtoplasma2012

The role of ATP-binding cassette transporters in bacterial pathogenicity.

Victoria G Lewis, Miranda P Ween, Christopher A McDevitt

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Protoplasma, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 115 citations in OpenAlex.

  1. Review
  2. Article
  3. Comparative genomics-based insights intoApplied and environmental microbiology · 2025
    Article
  4. Observational
  5. Article
  6. Proteomic profiling of zinc homeostasis mechanisms inbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Proteomic landscape of imipenem resistance inFrontiers in cellular and infection microbiology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Characterization Studies on theVeterinary sciences · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Victoria G LewisResearch Centre for Infectious Diseases, School of Molecular and Biomedical Science, University of Adelaide, Adelaide, South Australia, 5005, Australia.
Miranda P Ween
Christopher A McDevitt
University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ATP-binding cassette transporter superfamily is present in all three domains of life. This ubiquitous class of integral membrane proteins have diverse biological functions, but their fundamental role involves the unidirectional translocation of compounds across cellular membranes in an ATP coupled process. The importance of this class of proteins in eukaryotic systems is well established as typified by their association with genetic diseases and roles in the multi-drug resistance of cancer. In stark contrast, the ABC transporters of prokaryotes have not been exhaustively investigated due to the sheer number of different roles and organisms in which they function. In this review, we examine the breadth of functions associated with microbial ABC transporters in the context of their contribution to bacterial pathogenicity and virulence.

Indexed as

Amino Acid SequenceATP-Binding Cassette TransportersBacteriaBacterial ProteinsBiological TransportHumansMembrane Transport ProteinsATP-Binding Cassette TransportersBacterial ProteinsMembrane Transport Proteins

Identifiers

PMID22246051
OpenAlexW1975308719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.