ArticleThe Annals of thoracic surgery2012
The effect of mitral annuloplasty shape in ischemic mitral regurgitation: a finite element simulation.
Article in The Annals of thoracic surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 57 citations in OpenAlex.
- Simulated Effects of Acute Left Ventricular Myocardial Infarction on Mitral Regurgitation in an Ovine Model.Journal of biomechanical engineering · 2024Article
- Guidelines for mechanistic modeling and analysis in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2024Review
- A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State.Journal of biomechanical engineering · 2023Article
- Computational Modeling of the Subject-Specific Effects of Annuloplasty Ring Sizing on the Mitral Valve to Repair Functional Mitral Regurgitation.Annals of biomedical engineering · 2023Article
- Utilization of Engineering Advances for Detailed Biomechanical Characterization of the Mitral-Ventricular Relationship to Optimize Repair Strategies: A Comprehensive Review.Bioengineering (Basel, Switzerland) · 2023Review
- Numerical biomechanics modelling of indirect mitral annuloplasty treatments for functional mitral regurgitation.Royal Society open science · 2022Article
- New Insights into Valve Hemodynamics.Rambam Maimonides medical journal · 2020Review
- Virtual downsizing for decision support in mitral valve repair.International journal of computer assisted radiology and surgery · 2019Article
- Article
- Modelling mitral valvular dynamics-current trend and future directions.International journal for numerical methods in biomedical engineering · 2017Article
- A coupled mitral valve-left ventricle model with fluid-structure interaction.Medical engineering & physics · 2017Article
- Computational virtual evaluation of the effect of annuloplasty ring shape.International journal for numerical methods in biomedical engineering · 2017Article
- Finite Element Analysis of Patient-Specific Mitral Valve with Mitral Regurgitation.Cardiovascular engineering and technology · 2017Article
- Undersized Mitral Annuloplasty Increases Strain in the Proximal Lateral Left Ventricular Wall.The Annals of thoracic surgery · 2017Article
- Personalised computational cardiology: Patient-specific modelling in cardiac mechanics and biomaterial injection therapies for myocardial infarction.Heart failure reviews · 2016Review
- Neochord placement versus triangular resection in mitral valve repair: A finite element model.The Journal of surgical research · 2016Article
- Suture Forces for Closure of Transapical Transcatheter Aortic Valve Replacement: A Mathematical Model.The Journal of heart valve disease · 2016Article
- A Characteristic-Based Constitutive Law for Dispersed Fibers.Journal of biomechanical engineering · 2016Article
- Finite Element Modeling of Mitral Valve Repair.Journal of biomechanical engineering · 2016Review
- Residual Stress Impairs Pump Function After Surgical Ventricular Remodeling: A Finite Element Analysis.The Annals of thoracic surgery · 2015Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundUndersized mitral annuloplasty (MA) is the preferred surgical treatment for chronic ischemic mitral regurgitation. However, the preferred shape of undersized MA is unclear.
methodsA previously described finite element model of the left ventricle with mitral valve based on magnetic resonance images of a sheep with chronic ischemic mitral regurgitation after posterolateral myocardial infarction was used. Saddle-shape (Edwards Physio II) and asymmetric (IMR ETlogix) MA rings were digitized and meshed. Virtual annuloplasty was performed using virtual sutures to attach the MA ring. Left ventricular diastole and systole were performed before and after virtual MA of each type.
resultsBoth types of MA reduced the septolateral dimension of the mitral annulus and abolished mitral regurgitation. The asymmetric MA was associated with lower virtual suture force in the P2 region but higher force in P1 and P3 regions. Although both types of MA reduced fiber stress at the left ventricular base, fiber stress reduction after asymmetric MA was slightly greater. Neither type of MA affected fiber stress at the left ventricular equator or apex. Although both types of MA increased leaflet curvature and reduced leaflet stress, stress reduction with saddle-shape MA was slightly greater. Both MA types reduced stress on the mitral chordae.
conclusionsThe effects of saddle-shape and asymmetric MA rings are similar. Finite element simulations are a powerful tool that may reduce the need for animal and clinical trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.