Evidence map›Paper›PMID 22245165›Full record

ArticleGeneral hospital psychiatry

Onset and risk factors for anxiety and depression during the first 2 years after lung transplantation.

Mary Amanda Dew, Andrea F DiMartini, Annette J DeVito Dabbs, Kristen R Fox, Larissa Myaskovsky, Donna M Posluszny, Galen E Switzer, Rachelle A Zomak, Robert L Kormos, Yoshiya Toyoda

Abstract readComparative Study
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Telehealth interventions to improve outcomes in lung transplant recipients: Primary results of the INSPIRE-III randomized clinical trial.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025
    Trial
  5. Trial
  6. Psychosocial Predictors of Mortality Following Lung Transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2016
    Trial
  7. Trial
  8. Article
  9. Psychosocial challenges with transplantation.Current opinion in pulmonary medicine · 2026
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. A Mixed Methods Assessment of Home-Based Video Pretransplant Lung Education.Progress in transplantation (Aliso Viejo, Calif.) · 2022
    Article
  18. Article
  19. Non-pulmonary complications after lung transplantation: Part I.Indian journal of thoracic and cardiovascular surgery · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mary Amanda DewDepartment of Psychiatry, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, PA 15213, USA. dewma@upmc.edu
Andrea F DiMartini
Annette J DeVito Dabbs
Kristen R Fox
Larissa Myaskovsky
Donna M Posluszny
Galen E Switzer
Rachelle A Zomak
Robert L Kormos
Yoshiya Toyoda
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · USUPMC Hillman Cancer Center · US

Funding

MAJOR DEPRESSION, ANXIETY, AND LUNG TRANSPLANTATIONR01MH059229 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEW, MARY AMANDA · 1999 to 2003
$1.4M
Adherence to the HCT Medical Regimen: Influence of Cancer Patient-Cargiver DyadsK23CA149082 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI POSLUSZNY, DONNA M · 2011 to 2015
$531k
NCI NIH HHS K23 CA149082NIMH NIH HHS R01 MH059229
6 · The paper itself

Abstract

objectiveAnxiety disorders are prominent in chronic lung disease; lung transplant recipients may therefore also be at high risk for these disorders. We sought to provide the first prospective data on rates and risk factors for anxiety disorders as well as depressive disorders during the first 2 years after transplantation.

methodA total of 178 lung recipients and a comparison group (126 heart recipients) received psychosocial and Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition assessments at 2, 7, 12, 18 and 24 months posttransplant. Survival analysis determined onset rates and risk factors.

resultsThe panic disorder rate was higher (P<.05) in lung than heart recipients (18% vs. 8%). Lung and heart recipients did not differ on rates of transplant-related posttraumatic stress disorder (15% vs. 14%), generalized anxiety disorder (4% vs. 3%) or major depression (30% vs. 26%). Risk factors for disorders included pretransplant psychiatric history, female gender, longer wait for transplant, and early posttransplant health problems and psychosocial characteristics (e.g., poorer caregiver support and use of avoidant coping).

conclusionsHeightened vigilance for panic disorder in lung recipients and major depression in all cardiothoracic recipients is warranted. Strategies to prevent psychiatric disorder should target recipients based not only on pretransplant characteristics but on early posttransplant characteristics as well.

Indexed as

AdultAge of OnsetAnxiety DisordersFemaleHumansLung TransplantationMajor Depressive DisorderMaleMiddle AgedProportional Hazards ModelsRisk FactorsSurvival Analysis

Identifiers

PMID22245165
PMCPMC3288337
OpenAlexW2018940434

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.