ArticleRevista espanola de cardiologia (English ed.)2012
Melatonin and cardiovascular disease: myth or reality?
Article in Revista espanola de cardiologia (English ed.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03764020 (A Triple Blinded Randomized Controlled Trial of Oral Melatonin in Elevated Blood Pressure Individual), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Triple Blinded Randomized Controlled Trial of Oral Melatonin in Elevated Blood Pressure Individual (MRCTEBP)
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Incidence of adverse cardiovascular events in patients with insomnia: A systematic review and meta-analysis of real-world data.PloS one · 2023Pooled it
- Melatonin and the cardiovascular system in animals: systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2021Pooled it
- Neuroendocrine Stress Response in Acute Stroke: Physiological and Clinical Perspectives.Cureus · 2026Review
- Therapeutic Aspects of Melatonin-sirtuin Crosstalk: An Updated Review of Current Data Based on Cellular Mechanisms.Current drug targets · 2025Review
- Iris color and day-night changes in the sympathovagal ratio.Sleep and biological rhythms · 2024Article
- Melatonin Improves Levels of Zn and Cu in the Muscle of Diabetic Obese Rats.Pharmaceutics · 2021Article
- Melatonin as a therapy in cardiac ischemia-reperfusion injury: Potential mechanisms by which MT2 activation mediates cardioprotection.Journal of advanced research · 2021Article
- Article
- Review
- Melatonin and Parkinson Disease: Current Status and Future Perspectives for Molecular Mechanisms.Cellular and molecular neurobiology · 2020Review
- Altered Circadian Timing System-Mediated Non-Dipping Pattern of Blood Pressure and Associated Cardiovascular Disorders in Metabolic and Kidney Diseases.International journal of molecular sciences · 2018Review
- Peripheral and central effects of melatonin on blood pressure regulation.International journal of molecular sciences · 2014Review
- Cardioprotection and pharmacological therapies in acute myocardial infarction: Challenges in the current era.World journal of cardiology · 2014Review
- Hypertension and cardiovascular remodelling in rats exposed to continuous light: protection by ACE-inhibition and melatonin.Mediators of inflammation · 2014Article
- Potency of melatonin in living beings.Development & reproduction · 2013Article
- Molecular mechanisms of melatonin's inhibitory actions on breast cancers.Cellular and molecular life sciences : CMLS · 2013Review
- Diabetes and atherothrombosis: The circadian rhythm and role of melatonin in vascular protection.Diabetes & vascular disease researchReview
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
22245066What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.