ArticleBMC plant biology2012
A genomics approach to understanding the role of auxin in apple (Malus x domestica) fruit size control.
Article in BMC plant biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
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80 citing papers in PubMed.
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- A telomere-to-telomere gap-free genome of the new cultivar 'Zhongtian No. 5', combined with pan-genome analysis, aids in exploration and genetic enhancement of red clover (Horticulture research · 2026Article
- Identification of the Auxin Response Factor gene family in kernel consumption apricot and association analysis of related genes regulating fruit size in distant hybridization.BMC plant biology · 2026Article
- Application of Genome-Assisted Prediction (GAP) for Apple Fruit Weight.Plants (Basel, Switzerland) · 2025Article
- Growth regulation during early fruit development in apple (Malus × domestica Borkh.): a temporal event map of transcriptome and phytohormone changes.BMC plant biology · 2025Article
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- The triggering mechanism for predominant hormonal signal production in fleshy fruit ripening.Molecular horticulture · 2025Review
- Integrated endogenous hormones and transcriptome analysis contribute to fruit development related gene mining in Eriobotrya japonica.Scientific reports · 2025Article
- Comprehensive analysis of transcriptome and metabolome identified the key gene networks regulating fruit length in melon.BMC plant biology · 2025Article
- Increased genomic predictive ability in mango using GWAS-preselected variants and fixed-effect SNPs.Frontiers in plant science · 2025Article
- Article
- Genome-wide gene network uncover temporal and spatial changes of genes in auxin homeostasis during fruit development in strawberry (F. × ananassa).BMC plant biology · 2024Article
- Combined BSA-Seq and RNA-Seq to Identify Potential Genes Regulating Fruit Size in Bottle Gourd (Plants (Basel, Switzerland) · 2024Article
- The genetic basis of apple shape and size unraveled by digital phenotyping.G3 (Bethesda, Md.) · 2024Article
- Genomic analysis of fruit size and shape traits in apple: unveiling candidate genes through GWAS analysis.Horticulture research · 2024Article
- Advances in genomics and genome editing for improving strawberry (Frontiers in genetics · 2024Review
- Exploring the wild almond,Tree genetics & genomes · 2024Article
- Genetic variations inMolecular breeding : new strategies in plant improvement · 2024Article
20 more citing papers are in PubMed but not listed here.
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17 authors.
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Abstract
backgroundAuxin is an important phytohormone for fleshy fruit development, having been shown to be involved in the initial signal for fertilisation, fruit size through the control of cell division and cell expansion, and ripening related events. There is considerable knowledge of auxin-related genes, mostly from work in model species. With the apple genome now available, it is possible to carry out genomics studies on auxin-related genes to identify genes that may play roles in specific stages of apple fruit development.
resultsHigh amounts of auxin in the seed compared with the fruit cortex were observed in 'Royal Gala' apples, with amounts increasing through fruit development. Injection of exogenous auxin into developing apples at the start of cell expansion caused an increase in cell size. An expression analysis screen of auxin-related genes involved in auxin reception, homeostasis, and transcriptional regulation showed complex patterns of expression in each class of gene. Two mapping populations were phenotyped for fruit size over multiple seasons, and multiple quantitative trait loci (QTLs) were observed. One QTL mapped to a region containing an Auxin Response Factor (ARF106). This gene is expressed during cell division and cell expansion stages, consistent with a potential role in the control of fruit size.
conclusionsThe application of exogenous auxin to apples increased cell expansion, suggesting that endogenous auxin concentrations are at least one of the limiting factors controlling fruit size. The expression analysis of ARF106 linked to a strong QTL for fruit weight suggests that the auxin signal regulating fruit size could partially be modulated through the function of this gene. One class of gene (GH3) removes free auxin by conjugation to amino acids. The lower expression of these GH3 genes during rapid fruit expansion is consistent with the apple maximising auxin concentrations at this point.
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