Trial reportTrials2012
Hand washing with soap and water together with behavioural recommendations prevents infections in common work environment: an open cluster-randomized trial.
Trial report in Trials, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Probiotics in the Management of Acute Rotavirus Diarrhea in Bolivian Children: Randomized Double-blind, Controlled Trial Using Two Different Preparations
Kent State University / Price Chopper Wellness Promotion Study
Who cites it
30 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Physical interventions to interrupt or reduce the spread of respiratory viruses.The Cochrane database of systematic reviews · 2023Pooled it
- Interventions to increase personal protective behaviours to limit the spread of respiratory viruses: A rapid evidence review and meta-analysis.British journal of health psychology · 2022Pooled it
- The effect of hand hygiene promotion programs during epidemics and pandemics of respiratory droplet-transmissible infections on health outcomes: a rapid systematic review.BMC public health · 2021Pooled it
- Pooled it
- A Systematic Review for Effective Preventive Public Education of Respiratory Infection.International journal of environmental research and public health · 2021Pooled it
- Hand-washing promotion for preventing diarrhoea.The Cochrane database of systematic reviews · 2021Pooled it
- Physical interventions to interrupt or reduce the spread of respiratory viruses.The Cochrane database of systematic reviews · 2020Pooled it
- Hand washing promotion for preventing diarrhoea.The Cochrane database of systematic reviews · 2015Pooled it
- Hand hygiene and risk of influenza virus infections in the community: a systematic review and meta-analysis.Epidemiology and infection · 2014Pooled it
- The usefulness of hand washing during field training to prevent acute respiratory illness in a military training facility.Medicine · 2018Trial
- Intensified hand-hygiene campaign including soap-and-water wash may prevent acute infections in office workers, as shown by a recognized-exposure -adjusted analysis of a randomized trial.BMC infectious diseases · 2017Trial
- Trial
- Fermented Milk Consumption and Common Infections in Children Attending Day-Care Centers: A Randomized Trial.Journal of pediatric gastroenterology and nutrition · 2016Trial
- Impact of a Comprehensive Workplace Hand Hygiene Program on Employer Health Care Insurance Claims and Costs, Absenteeism, and Employee Perceptions and Practices.Journal of occupational and environmental medicine · 2016Trial
- Trial
- Outcomes of a pilot hand hygiene randomized cluster trial to reduce communicable infections among US office-based employees.Journal of occupational and environmental medicine · 2015Trial
- Sustained improvements in handwashing indicators more than 5 years after a cluster-randomised, community-based trial of handwashing promotion in Karachi, Pakistan.Tropical medicine & international health : TM & IH · 2013Trial
- Monitoring the Effectiveness of a Preschool Hand Hygiene Intervention Using Flow Cytometry to Determine the Reduction in the Microbiological Counts.International journal of environmental research and public health · 2025Article
- The effect of a hand hygiene intervention on the behaviour, practices and health of parents of preschool children in South Africa.Perspectives in public health · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHand hygiene is considered as an important means of infection control. We explored whether guided hand hygiene together with transmission-limiting behaviour reduces infection episodes and lost days of work in a common work environment in an open cluster-randomized 3-arm intervention trial.
methodsA total of 21 clusters (683 persons) were randomized to implement hand hygiene with soap and water (257 persons), with alcohol-based hand rub (202 persons), or to serve as a control (224 persons). Participants in both intervention arms also received standardized instructions on how to limit the transmission of infections. The intervention period (16 months) included the emergence of the 2009 influenza pandemic and the subsequent national hand hygiene campaign influencing also the control arm.
resultsIn the total follow-up period there was a 6.7% reduction of infection episodes in the soap-and water arm (p = 0.04). Before the onset of the anti-pandemic campaign, a statistically significant (p = 0.002) difference in the mean occurrence of infection episodes was observed between the control (6.0 per year) and the soap-and-water arm (5.0 per year) but not between the control and the alcohol-rub arm (5.6 per year). Neither intervention had a decreasing effect on absence from work.
conclusionsWe conclude that intensified hand hygiene using water and soap together with behavioural recommendations can reduce the occurrence of self-reported acute illnesses in common work environment. Surprisingly, the occurrence of reported sick leaves also increased in the soap-and water-arm.
trial registrationClinicalTrials.gov: NCT00981877 SOURCE OF
fundingThe Finnish Work Environment Fund and the National Institute for Health and Welfare.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.