Evidence map›Paper›PMID 22242890›Full record

ArticleExpert opinion on pharmacotherapy2012

Association between antidepressants and breast/ovarian cancer.

Chi-Un Pae

Abstract readComment
PubMed Publisher
In one paragraph

Article in Expert opinion on pharmacotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Chi-Un PaeThe Catholic University of Korea College of Medicine, Bucheon St. Mary's Hospital, Department of Psychiatry , 2 Sosa-Dong, Wonmi-Gu, Pucheon, Kyounggi-Do 420-717 , Republic of Korea. pae@catholic.ac.kr

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWomen are more vulnerable to the development of major depressive disorder (MDD) than men. Although several epidemiological studies have investigated the association between antidepressants and the risk of developing cancer, different methodologies were applied and as a result most of the results were inconsistent. A recent study by Cosgrove and colleagues at Harvard University investigated the relationship between prescriptions for antidepressants and breast/ovarian cancer, to determine whether such medications are associated with the development of cancer. AREAS COVERED: This paper discusses the relationship between the use of antidepressants and breast/ovarian cancer risk in the context of the potential limitations and significance of this recent research. EXPERT OPINION: Clinicians might need to be vigilant when treating female patients who require antidepressants, particularly those with other clinical risk factors in relation to breast/ovarian cancer; although more data will be necessary to evaluate the exact association between antidepressants and the development of such cancers.

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.