ArticleAnalytical chemistry2012
Use of negative dielectrophoresis for selective elution of protein-bound particles.
Article in Analytical chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- High Sensitivity Extended Nano-Coulter Counter for Detection of Viral Particles and Extracellular Vesicles.Analytical chemistry · 2023Article
- A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions.Microsystems & nanoengineering · 2023Article
- Study on non-bioparticles andRSC advances · 2020Article
- A review of polystyrene bead manipulation by dielectrophoresis.RSC advances · 2019Review
- Automated Dielectrophoretic Tweezers-Based Force Spectroscopy System in a Microfluidic Device.Sensors (Basel, Switzerland) · 2017Article
- Microfluidic and Nanofluidic Resistive Pulse Sensing: A Review.Micromachines · 2017Review
- Portable Cytometry Using Microscale Electronic Sensing.Sensors and actuators. B, Chemical · 2016Article
- A bead-based fluorescence immunosensing technique enabled by the integration of Förster resonance energy transfer and optoelectrokinetic concentration.Biomicrofluidics · 2016Article
- A hybrid dielectrophoretic system for trapping of microorganisms from water.Biomicrofluidics · 2015Article
- Multiplexed actuation using ultra dielectrophoresis for proteomics applications: a comprehensive electrical and electrothermal design methodology.Lab on a chip · 2014Article
- Depletion of cells and abundant proteins from biological samples by enhanced dielectrophoresis.Sensors and actuators. B, Chemical · 2014Article
- Smart surface for elution of protein-protein bound particles: nanonewton dielectrophoretic forces using atomic layer deposited oxides.Analytical chemistry · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
In this paper with the aid of negative dielectrophoresis force in conjunction with shear force and at an optimal sodium hydroxide concentration we demonstrated a switchlike functionality to elute specifically bound beads from the surface. At an optimal flow rate and sodium hydroxide concentration, negative dielectrophoresis turned on results in bead detachment, whereas when negative dielectrophoresis is off, the beads remain attached. This platform offers the potential for performing a bead-based multiplexed assay where in a single channel various regions are immobilized with a different antibody, each targeting a different antigen. To develop the proof of concept and to demonstrate the switchlike functionality in eluting specifically bound beads from the surface we looked at two different protein interactions. We chose interactions that were in the same order of magnitude in strength as typical antibody-antigen interactions. The first was protein G-IgG interaction, and the second was the interaction between anti-IgG and IgG.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.