ArticlePloS one2011
Role of conserved non-coding regulatory elements in LMW glutenin gene expression.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 34 citations in OpenAlex.
- De novo annotation reveals transcriptomic complexity across the hexaploid wheat pan-genome.Nature communications · 2025Article
- Activation of the native PHYTOENE SYNTHASE 1 promoter by modifying near-miss cis-acting elements induces carotenoid biosynthesis in embryogenic rice callus.Plant cell reports · 2024Article
- Storage protein activator controls grain protein accumulation in bread wheat in a nitrogen dependent manner.Scientific reports · 2023Article
- Transcriptome and Proteome Analysis Revealed the Influence of High-Molecular-Weight Glutenin Subunits (HMW-GSs) Deficiency on Expression of Storage Substances and the Potential Regulatory Mechanism of HMW-GSs.Foods (Basel, Switzerland) · 2023Article
- Wheat DOF transcription factors TaSAD and WPBF regulate glutenin gene expression in cooperation with SPA.PloS one · 2023Article
- Wheat Quality Formation and Its Regulatory Mechanism.Frontiers in plant science · 2022Review
- A novel NAC family transcription factor SPR suppresses seed storage protein synthesis in wheat.Plant biotechnology journal · 2021Article
- Genomic and functional genomics analyses of gluten proteins and prospect for simultaneous improvement of end-use and health-related traits in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Review
- Evaluation of the mature grain phytase candidate HvPAPhy_a gene in barley (Hordeum vulgare L.) using CRISPR/Cas9 and TALENs.Plant molecular biology · 2017Article
- Functional Characterization of TaFUSCA3, a B3-Superfamily Transcription Factor Gene in the Wheat.Frontiers in plant science · 2017Article
- Multiple elements controlling the expression of wheat high molecular weight glutenin paralogs.Functional & integrative genomics · 2015Article
- Conserved cis-regulatory modules in promoters of genes encoding wheat high-molecular-weight glutenin subunits.Frontiers in plant science · 2014Article
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- Comparative proteomic analysis of the effect of temperature and fertilizer on gliadin and glutenin accumulation in the developing endosperm and flour from Triticum aestivum L. cv. Butte 86.Proteome science · 2013Article
- Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcriptional regulation of LMW glutenin genes were investigated in-silico, using publicly available gene sequences and expression data. Genes were grouped into different LMW glutenin types and their promoter profiles were determined using cis-acting regulatory elements databases and published results. The various cis-acting elements belong to some conserved non-coding regulatory regions (CREs) and might act in two different ways. There are elements, such as GCN4 motifs found in the long endosperm box that could serve as key factors in tissue-specific expression. Some other elements, such as the AACA/TA motifs or the individual prolamin box variants, might modulate the level of expression. Based on the promoter sequences and expression characteristic LMW glutenin genes might be transcribed following two different mechanisms. Most of the s- and i-type genes show a continuously increasing expression pattern. The m-type genes, however, demonstrate normal distribution in their expression profiles. Differences observed in their expression could be related to the differences found in their promoter sequences. Polymorphisms in the number and combination of cis-acting elements in their promoter regions can be of crucial importance in the diverse levels of production of single LMW glutenin gene types.
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