ArticleAJNR. American journal of neuroradiology2012
Correlation of apparent diffusion coefficient at 3T with prognostic parameters of retinoblastoma.
Article in AJNR. American journal of neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diffusion-weighted MRI for predicting treatment response in patients with nasopharyngeal carcinoma: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Optic disc drusen: a systematic review : Up-to-date and future perspective.International ophthalmology · 2020Pooled it
- The apparent diffusion coefficient as a potential radiological biomarker of malignant transformation in retinoblastoma: a case report.Pediatric radiology · 2026Article
- Comparison of HASTE versus EPI-Based DWI for Retinoblastoma and Correlation with Prognostic Histopathologic Parameters.AJNR. American journal of neuroradiology · 2024Article
- Role of apparent diffusion map in the evaluation of retinoblastoma.Arquivos brasileiros de oftalmologia · 2024Observational
- Identification of immune-related gene signature for predicting prognosis in uterine corpus endometrial carcinoma.Scientific reports · 2023Article
- Multi-parametric arterial spin labeling and diffusion-weighted imaging of paranasal sinuses masses.Oral radiology · 2023Article
- Carotid disease and retinal optical coherence tomography angiography parameters in patients with non-arteritic anterior ischemic optic neuropathy.International ophthalmology · 2022Observational
- The value of the apparent diffusion coefficient value in the Liver Imaging Reporting and Data System (LI-RADS) version 2018.Polish journal of radiology · 2022Article
- A descriptive neuroimaging study of retinoblastoma in children: magnetic resonance imaging features.Polish journal of radiology · 2022Article
- Early Response to Chemotherapy in Malignant Pleural Mesothelioma Evaluated Using Diffusion-Weighted Magnetic Resonance Imaging: Initial Observations.JTO clinical and research reports · 2021Article
- Diffusion tensor imaging of the spleen in prediction and grading of esophageal varices in cirrhotic children with portal hypertension.Japanese journal of radiology · 2021Article
- Bone-related disorders of the jaw: A clinico-radiological diagnostic algorithm.The neuroradiology journal · 2021Article
- Multi-parametric arterial spin labeling and diffusion-weighted imaging in differentiation of metastatic from reactive lymph nodes in head and neck squamous cell carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Article
- Correlations between apparent diffusion coefficient values of WB-DWI and clinical parameters in multiple myeloma.BMC medical imaging · 2021Article
- Overexpressing PTTG family genes predict poor prognosis in kidney renal clear cell carcinoma.World journal of surgical oncology · 2021Article
- MR and CT imaging features of sino-nasal organized hematomas.Oral radiology · 2021Article
- The role of diffusion tensor imaging of the liver in children with autoimmune hepatitis.Polish journal of radiology · 2021Article
- Novel observations in choroidal osteoma by multispectral imaging: a pilot case series.International ophthalmology · 2020Article
- A Potential Role For Apparent Diffusion Coefficient in the Diagnosis of Trilateral Retinoblastoma.Journal of pediatric hematology/oncology · 2020Article
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Abstract
background and purposePathologic prognostic parameters for retinoblastoma have been defined. Our purpose was to correlate ADC values at 3T with prognostic parameters of retinoblastoma. MATERIALS AND
methodsThis study included 72 children (30 boys and 42 girls, mean age 19 ± 2.6 months) with retinoblastoma. Pretreatment diffusion-weighted MR imaging was performed on a 3T scanner with b factors of 0, 500, and 1000 seconds/mm(2). ADC values were calculated and pathologic specimens were analyzed. ADC values of the tumors were then correlated with prognostic parameters, including degree of histologic differentiation, tumor size, bilaterality, choroidal invasion, and optic nerve extension.
resultsThe mean ADC value of retinoblastoma was 0.49 ± 0.12 × 10(-3) mm(2)/s. The ADC values of well- and moderately differentiated tumors were significantly different (P = .007) from poorly and undifferentiated retinoblastoma. There was also a significant difference in the ADC value among small, medium, and large tumors (P = .015), as well as between unilateral and bilateral retinoblastoma (P = .001), and this was independent of the degree of differentiation. The ADC value was also significantly lower (P = .003) when optic nerve invasion was present. There was no correlation of ADC value with growth pattern or choroidal invasion (P = .640 and 0.661, respectively). The ADC value of retinoblastoma was well correlated with the degree of differentiation of the tumor (r = 0.87, P = .007) and inversely correlated with the size of the tumor (r = -0.68, P = .015).
conclusionsADC correlated with some of the accepted parameters of poor prognosis for retinoblastoma and may serve as a noninvasive prognostic parameter for assessment of newly diagnosed retinoblastoma.
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