ArticleBMJ open2012
The longitudinal prevalence of MRSA in care home residents and the effectiveness of improving infection prevention knowledge and practice on colonisation using a stepped wedge study design.
Article in BMJ open, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Approaches to multidrug-resistant organism prevention and control in long-term care facilities for older people: a systematic review and meta-analysis.Antimicrobial resistance and infection control · 2022Pooled it
- Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014.Trials · 2015Pooled it
- Infection control strategies for preventing the transmission of meticillin-resistant Staphylococcus aureus (MRSA) in nursing homes for older people.The Cochrane database of systematic reviews · 2013Pooled it
- MRSA carriage rate among dental healthcare personnel: amulticentric cross-sectional study.Acta odontologica latinoamericana : AOL · 2026Article
- Article
- Presence of Methicillin-ResistantTropical medicine and infectious disease · 2021Review
- Transmission and Long-Term Colonization Patterns ofInternational journal of environmental research and public health · 2020Article
- Relationship between biofilm gene expression with antimicrobial resistance pattern and clinical specimen type based on sequence types (STs) of methicillin-resistant S. aureus.Molecular biology reports · 2020Article
- Screening for Methicillin-resistantJournal of occupational medicine and toxicology (London, England) · 2017Article
- Communicating the Risk of MRSA: The Role of Clinical Practice, Regulation and Other Policies in Five European Countries.Frontiers in public health · 2017Article
- Making infection prevention education interactive can enhance knowledge and improve outcomes: Results from the Targeted Infection Prevention (TIP) Study.American journal of infection control · 2016Article
- Transmission of methicillin-resistant Staphylococcus aureus in long-term care facilities and their related healthcare networks.Genome medicine · 2016Observational
- Stepped wedge cluster randomised trials: a review of the statistical methodology used and available.BMC medical research methodology · 2016Review
- Review
- Article
- Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies.Trials · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives To determine the prevalence and health outcomes of meticillin-resistant Staphylococcus aureus (MRSA) colonisation in elderly care home residents. To measure the effectiveness of improving infection prevention knowledge and practice on MRSA prevalence. Setting Care homes for elderly residents in Leeds, UK. Participants Residents able to give informed consent. Design A controlled intervention study, using a stepped wedge design, comprising 65 homes divided into three groups. Baseline MRSA prevalence was determined by screening the nares of residents (n=2492). An intervention based upon staff education and training on hand hygiene was delivered at three different times according to group number. Scores for three assessment methods, an audit of hand hygiene facilities, staff hand hygiene observations and an educational questionnaire, were collected before and after the intervention. After each group of homes received the intervention, all participants were screened for MRSA nasal colonisation. In total, four surveys took place between November 2006 and February 2009. Results MRSA prevalence was 20%, 19%, 22% and 21% in each survey, respectively. There was a significant improvement in scores for all three assessment methods post-intervention (p≤0.001). The intervention was associated with a small but significant increase in MRSA prevalence (p=0.023). MRSA colonisation was associated with previous and subsequent MRSA infection but was not significantly associated with subsequent hospitalisation or mortality. Conclusions The intervention did not result in a decrease in the prevalence of MRSA colonisation in care home residents. Additional measures will be required to reduce endemic MRSA colonisation in care homes.
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Registered trials
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