Evidence map›Paper›PMID 22237925›Full record

ArticleMycopathologia2012

Chemical composition and antifungal activity of essential oils and supercritical CO2 extracts of Apium nodiflorum (L.) Lag.

Andrea Maxia, Danilo Falconieri, Alessandra Piras, Silvia Porcedda, Bruno Marongiu, Maria Assunta Frau, Maria J Gonçalves, Célia Cabral, Carlos Cavaleiro, Lígia Salgueiro

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Article in Mycopathologia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Protective Effects of Anethole inAntioxidants (Basel, Switzerland) · 2024
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  8. Utilization of Nutmeg (Molecules (Basel, Switzerland) · 2020
    Article
  9. Article
  10. Article
  11. Formulation and Characterization of Potential Antifungal Oleogel with Essential Oil of Thyme.Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
  12. Review
  13. Commercial Essential Oils as Potential Antimicrobials to Treat Skin Diseases.Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Andrea MaxiaDipartimento della Scienza della Vita e dell'Ambiente-Macrosezione di Botanica e Orto Botanico, Università degli Studi di Cagliari, Viale Sant' Ignazio, 09123, Cagliari, Italy.
Danilo Falconieri
Alessandra Piras
Silvia Porcedda
Bruno Marongiu
Maria Assunta Frau
Maria J Gonçalves
Célia Cabral
Carlos Cavaleiro
Lígia Salgueiro
University of Cagliari · ITUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aerial parts of Apium nodiflorum collected in Portugal and Italy were submitted to hydrodistillation; also a supercritical fluid extract was obtained from Italian plants. The extracts were analyzed by GC and GC/MS. Both essential oils, obtained from Portuguese and Italian plants, posses high content of phenylpropanoids (51.6 vs. 70.8%); in the former, the percentage split in myristicin (29.1%) and dillapiol (22.5%), whereas in the latter, the total percentage is only of dillapiol (70.8%). The co-occurrence of myristicin and dillapiol is frequent because dillapiol results from enzymatic methoxylation of myristicin. Antimicrobial activity of phenylpropanoids has been patented, what suggest the potential of plants with high amounts of these compounds. Minimal inhibitory concentration (MIC) and minimal lethal concentration, determined according to NCCLS, were used to evaluate the antifungal activity of the essential oils against yeasts, Aspergillus species and dermatophytes. Essential oils exhibited higher antifungal activity than other Apiaceae against dermatophytes, with MIC ranging from 0.04 to 0.32 μl/ml. These results support the potential of A. nodiflorum oil in the treatment of dermatophytosis and candidosis.

Indexed as

ApiaceaeArthrodermataceaeAspergillusCarbon DioxideChromatography, Supercritical FluidGas Chromatography-Mass SpectrometryItalyMicrobial Sensitivity TestsOils, VolatilePlant ExtractsPortugalCarbon DioxideOils, VolatilePlant Extracts

Identifiers

PMID22237925
OpenAlexW1980429588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.