ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2012
Vitamin D status and physical activity interact to improve bone mass in adolescents. The HELENA Study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- A systematic review of vitamin D status in southern European countries.European journal of nutrition · 2018Pooled it
- Review
- Paediatric cancer survivors: lean mass attenuates negative impact of watching television on bone.Pediatric research · 2025Article
- Associations of linear growth and weight gain in the first 2 years with bone mass at 4 years of age in children in Dhaka, Bangladesh.Public health nutrition · 2024Article
- The independent and interactive associations of physical activity intensity and vitamin D status with bone mineral density in prepubertal children: the PANIC Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- Hypovitaminosis D in Young Basketball Players: Association with Jumping and Hopping Performance Considering Gender.International journal of environmental research and public health · 2021Article
- Vitamin D Status in Adolescents during COVID-19 Pandemic: A Cross-Sectional Comparative Study.Nutrients · 2021Article
- Demographic Differences and Trends of Vitamin D Levels Among the Teenaged Girls in Balochistan.Cureus · 2020Article
- The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial.BMC public health · 2020Article
- May Young Elite Cyclists Have Less Efficient Bone Metabolism?Nutrients · 2019Article
- Physical activity but not sedentary time is associated with vitamin D status in adolescents: study of cardiovascular risk in adolescents (ERICA).European journal of clinical nutrition · 2019Article
- Article
- Fat Mass Is Associated with Serum 25-Hydroxyvitamin D Concentration Regardless of Body Size in Men.Nutrients · 2018Article
- Vitamin D status of Icelandic children and its influence on bone accrual.Journal of bone and mineral metabolism · 2016Article
- 25-Hydroxyvitamin D insufficiency discriminates cardiovascular risk factors accumulation in peri-pubertal boys undergoing overweight screening.Endocrine · 2016Article
- Article
- The prevalence and determinants of use of vitamin D supplements among children in Alberta, Canada: a cross-sectional study.BMC public health · 2015Article
- The influence of dairy consumption, sedentary behaviour and physical activity on bone mass in Flemish children: a cross-sectional study.BMC public health · 2015Article
- Effect of a program of short bouts of exercise on bone health in adolescents involved in different sports: the PRO-BONE study protocol.BMC public health · 2015Article
- Physical activity and bone health in schoolchildren: the mediating role of fitness and body fat.PloS one · 2015Article
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Authors and funding
13 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledThe effects of vitamin D concentrations on bone mineral content in adolescents are still unclear. Vitamin D and physical activity (PA) may interact to determine bone mineral content (BMC) in two possible directions; 25(OH)D sufficiency levels improve BMC only in active adolescents, or PA increases BMC in individuals with replete vitamin D levels.
introductionThe effects of suboptimal 25-hydroxycholecalciferol (25(OH)D) concentrations on BMC in adolescents are still unclear. The main aim of this study was to evaluate the influence of 25(OH)D on BMC in adolescents, considering the effect of body composition, sex, age, Tanner stage, season, calcium and vitamin D intakes, physical fitness and PA.
methodsSerum 25(OH)D concentrations, anthropometric measurements, dual energy X-ray absorptiometry measurements, calcium and vitamin D intakes, PA and physical fitness were obtained in 100 Spanish adolescents (47 males), aged 12.5-17.5 years, within the framework of the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study. Relations were examined using ANCOVA and regression analyses including BMC as dependent variable.
resultsLinear regression of BMC suggested that 25(OH)D concentrations independently influenced total and leg BMC after controlling for age, sex, lean mass, seasonality and calcium intake (B = 0.328, p < 0.05, and B = 0.221, p < 0.05, respectively) in the physically active group. No significant influence of 25(OH)D concentrations on BMC was observed in the inactive group. Significant effect was shown between the interaction of 25(OH)D and PA on BMC for the total body and legs (both p < 0.05).
conclusionsVitamin D and PA may interact to determine BMC. 25(OH)D sufficiency levels improve bone mass only in active adolescents, or PA has a positive influence on BMC in individuals with replete vitamin D levels.
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