ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2012
Growth from birth to adulthood and peak bone mass and density data from the New Delhi Birth Cohort.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Association between maternal smoking and child bone mineral density: a systematic review and meta-analysis.Environmental science and pollution research international · 2020Pooled it
- Steady Growth in Early Infancy Is Associated with Greater Anthropometry in Indian Children Born Low Birth Weight at Term.The Journal of nutrition · 2019Trial
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- Associations of linear growth and weight gain in the first 2 years with bone mass at 4 years of age in children in Dhaka, Bangladesh.Public health nutrition · 2024Article
- Potential influences on optimizing long-term musculoskeletal health in children and adolescents with X-linked hypophosphatemia (XLH).Orphanet journal of rare diseases · 2022Review
- Prevalence of Sarcopenia and Relationships Between Muscle and Bone in Indian Men and Women.Calcified tissue international · 2021Article
- Urinary Metabolic Profiling via LC-MS/MS Reveals Impact of Bovine Lactoferrin on Bone Formation in Growing SD Rats.Nutrients · 2020Article
- Bone Metabolism in Adolescents and Adults Undergoing Roux-En-Y Gastric Bypass: a Comparative Study.Obesity surgery · 2019Article
- Analysis of lifestyle and bone mineralization in a population of Spanish young adults.Colombia medica (Cali, Colombia) · 2018Article
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- Ethnic Differences in Peripheral Skeletal Development Among Urban South African Adolescents: A Ten-Year Longitudinal pQCT Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017Article
- Childhood growth predicts higher bone mass and greater bone area in early old age: findings among a subgroup of women from the Helsinki Birth Cohort Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Effects of doxorubicin administration on bone strength and quality in sedentary and physically active Wistar rats.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Article
- Skeletal Maturation and Mineralisation of Children with Moderate to Severe Spastic Quadriplegia.Journal of clinical and diagnostic research : JCDR · 2016Article
- Bone health and HIV in resource-limited settings: a scoping review.Current opinion in HIV and AIDS · 2016Article
- Body mass index at 11 years and bone mass at age 18: path analysis within the 1993 Pelotas (Brazil) birth cohort study.BMC musculoskeletal disorders · 2015Article
- Adolescent undernutrition and early adulthood bone mass in an urbanizing rural community in India.Archives of osteoporosis · 2015Article
- Life-course determinants of bone mass in young adults from a transitional rural community in India: the Andhra Pradesh Children and Parents Study (APCAPS).The American journal of clinical nutrition · 2014Article
- Growth from birth to adulthood and bone phenotype in early old age: a British birth cohort study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2014Article
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Authors and funding
14 authors at 9 institutions in 2 countries.
Funding
Abstract
unlabelledGrowth in early life may predict adult bone health. Our data showed that greater height and body mass index (BMI) gain in utero and infancy are associated with higher peak bone mass, and greater BMI gain in childhood/adolescence with higher peak bone density. These associations are mediated by attained adult height and BMI.
introductionTo study the relationship of height and BMI during childhood with adult bone mineral content (BMC), areal density (aBMD) and apparent density (BMAD, estimated volumetric density).
methodsParticipants comprised 565 men and women aged 33-39 years from the New Delhi Birth Cohort, India, whose weight and height were recorded at birth and annually during infancy (0-2 years), childhood (2-11 years) and adolescence (11 years-adult). Lumbar spine, femoral neck and forearm BMC and aBMD were measured using dual X-ray absorptiometry; lumbar spine and femoral neck BMAD were calculated.
resultsBirth length, and height and height gain during infancy, childhood and adolescence were positively correlated with adult BMC (p≤0.01 all sites except birth length with femoral neck). Correlations increased with height from birth to 6 years, then remained constant for later height measurements. There were no associations with BMAD. BMI at birth, and during childhood and adolescence was also positively correlated with BMC (p < 0.01 all sites). BMI at 11 years, and BMI gain in childhood and adolescence, were correlated with aBMD and BMAD (p < 0.001 for all); these correlations strengthened with increasing age of BMI measurement. The associations with height and BMI in early life became non-significant after adjustment for adult height and BMI.
conclusionsGreater skeletal growth and BMI gain in utero and during infancy are associated with higher peak BMC, and greater BMI gain in childhood and adolescence is associated with higher peak aBMD and BMAD. These associations are mediated by the attainment of adult height and BMI, respectively.
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