ArticleThe ISME journal2012
In situ proteo-metabolomics reveals metabolite secretion by the acid mine drainage bio-indicator, Euglena mutabilis.
Article in The ISME journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Systematic Review of Multi-Omics Approaches to Investigate Toxicological Effects in Macrophages.International journal of molecular sciences · 2020Pooled it
- Integrated transcriptomic and hormonomic insights into cadmium tolerance of aMicrobiology (Reading, England) · 2026Article
- PMconv: How to Compare Proteomes and Metabolomes?International journal of molecular sciences · 2026Article
- Euglena mutabilis exists in a FAB consortium with microbes that enhance cadmium tolerance.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Microalgal photoautotrophic growth induces pH decrease in the aquatic environment by acidic metabolites secretion.Biotechnology for biofuels and bioproducts · 2022Article
- Community RNA-Seq: multi-kingdom responses to living versus decaying roots in soil.ISME communications · 2021Article
- Acid Mine Drainage as Habitats for Distinct Microbiomes: Current Knowledge in the Era of Molecular and Omic Technologies.Current microbiology · 2020Review
- Microalgae-bacteria biofilms: a sustainable synergistic approach in remediation of acid mine drainage.Applied microbiology and biotechnology · 2018Review
- Dynamic substrate preferences predict metabolic properties of a simple microbial consortium.BMC bioinformatics · 2017Article
- Meneco, a Topology-Based Gap-Filling Tool Applicable to Degraded Genome-Wide Metabolic Networks.PLoS computational biology · 2017Article
- Spatial Distribution of Eukaryotic Communities Using High-Throughput Sequencing Along a Pollution Gradient in the Arsenic-Rich Creek Sediments of Carnoulès Mine, France.Microbial ecology · 2016Article
- (1)H NMR metabolomic study of auxotrophic starvation in yeast using Multivariate Curve Resolution-Alternating Least Squares for Pathway Analysis.Scientific reports · 2016Article
- Proteomic tools to decipher microbial community structure and functioning.Environmental science and pollution research international · 2015Review
- Thiomonas sp. CB2 is able to degrade urea and promote toxic metal precipitation in acid mine drainage waters supplemented with urea.Frontiers in microbiology · 2015Article
- Systems-based approaches to unravel multi-species microbial community functioning.Computational and structural biotechnology journal · 2015Review
- Article
- Novel and unexpected bacterial diversity in an arsenic-rich ecosystem revealed by culture-dependent approaches.Biology direct · 2012Article
- Amylases without known homologues discovered in an acid mine drainage: significance and impact.Scientific reports · 2012Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Euglena mutabilis is a photosynthetic protist found in acidic aquatic environments such as peat bogs, volcanic lakes and acid mine drainages (AMDs). Through its photosynthetic metabolism, this protist is supposed to have an important role in primary production in such oligotrophic ecosystems. Nevertheless, the exact contribution of E. mutabilis in organic matter synthesis remains unclear and no evidence of metabolite secretion by this protist has been established so far. Here we combined in situ proteo-metabolomic approaches to determine the nature of the metabolites accumulated by this protist or potentially secreted into an AMD. Our results revealed that the secreted metabolites are represented by a large number of amino acids, polyamine compounds, urea and some sugars but no fatty acids, suggesting a selective organic matter contribution in this ecosystem. Such a production may have a crucial impact on the bacterial community present on the study site, as it has been suggested previously that prokaryotes transport and recycle in situ most of the metabolites secreted by E. mutabilis. Consequently, this protist may have an indirect but important role in AMD ecosystems but also in other ecological niches often described as nitrogen-limited.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.