ArticleInfection2012
Pro-atrial natriuretic peptide (pro-ANP) level in patients with severe sepsis and septic shock: prognostic and diagnostic significance.
Article in Infection, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Current and novel biomarkers in cardiogenic shock.European journal of heart failure · 2025Review
- The Potential of Cardiac Biomarkers in Differentiating Disease Subtypes in Patients with Systemic Sclerosis: Focus on GDF15, MR-pro ANP, and suPAR.International journal of molecular sciences · 2025Article
- Circulating corin concentration is associated with risk of mortality and acute kidney injury in critically ill patients.Scientific reports · 2024Article
- Soluble neprilysin and survival in critically ill patients.ESC heart failure · 2022Observational
- Electroanalytical point-of-care detection of gold standard and emerging cardiac biomarkers for stratification and monitoring in intensive care medicine - a review.Mikrochimica acta · 2022Review
- Mid-regional pro-adrenomedullin for diagnosing evolution after cardiac surgery in newborns: the PRONEW study.European journal of pediatrics · 2022Article
- An analysis of urine and serum amino acids in critically ill patients upon admission by means of targeted LC-MS/MS: a preliminary study.Scientific reports · 2021Article
- Pro-atrial natriuretic peptide and pro-adrenomedullin before cardiac surgery in children. Can we predict the future?PloS one · 2020Article
- Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients.Journal of translational medicine · 2019Article
- Prognostic value of biomarkers after cardiopulmonary bypass in pediatrics: The prospective PANCAP study.PloS one · 2019Observational
- Plasma pro-atrial natriuretic peptide to indicate fluid balance during cystectomy: a prospective observational study.BMJ open · 2016Observational
- Prognostic Value of Adrenomedullin and Natriuretic Peptides in Uroseptic Patients Induced by Ureteroscopy.Mediators of inflammation · 2016Article
- Observational
- Sepsis outside intensive care unit: the other side of the coin.Infection · 2015Review
- Cross-talk between HPA-axis-increased glucocorticoids and mitochondrial stress determines immune responses and clinical manifestations of patients with sepsis.Redox report : communications in free radical research · 2015Review
- Procalcitonin levels in fresh serum and fresh synovial fluid for the differential diagnosis of knee septic arthritis from rheumatoid arthritis, osteoarthritis and gouty arthritis.Experimental and therapeutic medicine · 2014Article
- Biomarkers in sepsis.Current infectious disease reports · 2013Article
- Article
- The potential impact of biomarker-guided triage decisions for patients with urinary tract infections.Infection · 2013Article
- New markers in pneumonia.Clinica chimica acta; international journal of clinical chemistry · 2013Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo establish the prognostic and discriminative value of the pro-atrial natriuretic peptide (pro-ANP) level in patients with severe sepsis or septic shock. PATIENTS AND
methodsAn observational and prospective study was conducted on 50 critically ill patients with severe sepsis or septic shock. Measurements of the level of procalcitonin (PCT) and mid-regional pro-ANP were determined in the serum of patients with commercially available immunoluminometric tests.
resultsThe median pro-ANP level was significantly higher in non-survivors than in survivors (P < 0.05) on all consecutive days. No significant differences in the pro-ANP levels were observed in patients with severe sepsis and septic shock. There was a strong correlation between the PCT and pro-ANP levels on admission in non-survivors and in septic shock patients (r = 0.56, P = 0.007 and r = 0.43, P = 0.02, respectively).
conclusionspro-ANP evaluated in severe sepsis and septic shock patients is a valuable prognostic biomarker, but, in contrast to PCT, which is routinely used as a diagnostic marker of severe sepsis and septic shock, it does not possess diagnostic and discriminative value.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.