Evidence map›Paper›PMID 2223703›Full record

Trial reportThe British journal of ophthalmology1990

Topical timolol and serum lipoproteins.

J West, S Longstaff

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in The British journal of ophthalmology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Topical timolol and serum lipoproteins.The British journal of ophthalmology · 1992
    Article
  3. Topical beta blockers and serum lipoproteins.The British journal of ophthalmology · 1991
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

J WestDepartment of Ophthalmology, Royal Hallamshire Hospital, Sheffield.
S Longstaff
Royal Hallamshire Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral timolol taken for the treatment of systemic hypertension has been shown to affect adversely serum lipoprotein levels. In a 15-week study on 19 patients topical timolol therapy for raised intraocular pressure was found to have no significant adverse effect on serum lipoprotein levels. This is reassuring in view of the large number of patients on this form of long term therapy, and selection of the type of beta blocker to use should not be influenced by lipid changes associated with the oral form of the drug.

Indexed as

Administration, TopicalAgedAged, 80 and overFemaleGlaucomaHumansLipoproteinsMaleMiddle AgedOcular HypertensionProspective StudiesTimololLipoproteinsTimolol

Identifiers

PMID2223703
PMCPMC1042253
OpenAlexW1971078035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.