Evidence map›Paper›PMID 22236769›Full record

ArticleBiophysical chemistry2012

Conformation of poly-L-glutamate is independent of ionic strength.

Kan Xiong, Lu Ma, Sanford A Asher

Abstract read
In one paragraph

Article in Biophysical chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kan XiongDepartment of Chemistry, University of Pittsburgh, PA 15260, USA.
Lu Ma
Sanford A Asher

Funding

Ultrahigh Throughput Deep UV Raman Spectrometer for Probing Protein StructureR01EB009089 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ASHER, SANFORD A. · 2008 to 2011
$1.3M
NIBIB NIH HHS 1R01EB009089NIBIB NIH HHS R01 EB009089
6 · The paper itself

Abstract

CD and UV resonance Raman measurements surprisingly find that the charge screening of even 2 M concentrations of NaCl and KCl does not alter the unfolded PPII and 2.5(1)-helix conformations of poly-L-glutamate. These salts appear to be excluded from the region between the side chain charges and the peptide backbone. Furthermore, no direct ion pairing occurs between these salts and the side chain carboxylates.

Indexed as

Circular DichroismModels, MolecularOsmolar ConcentrationPolyglutamic AcidPotassium ChlorideProtein Structure, SecondarySodium ChlorideSpectrophotometry, UltravioletSpectrum Analysis, RamanPolyglutamic AcidPotassium ChlorideSodium Chloride

Identifiers

PMID22236769
PMCPMC3288237

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.