Evidence map›Paper›PMID 22236527›Full record

Trial reportJournal of biomechanics2012

Activation and aponeurosis morphology affect in vivo muscle tissue strains near the myotendinous junction.

Niccolo M Fiorentino, Frederick H Epstein, Silvia S Blemker

Abstract readClinical Trial
In one paragraph

Trial report in Journal of biomechanics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Review
  20. Hamstring injuries: prevention and treatment-an update.British journal of sports medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Niccolo M FiorentinoDepartment of Mechanical & Aerospace Engineering, University of Virginia, Charlottesville, VA 22904, USA.
Frederick H Epstein
Silvia S Blemker

Funding

MRI of Myocardial Function in Post-Infarct Knockout MiceR01EB001763 · NIBIB · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI EPSTEIN, FREDERICK H · 2003 to 2020
$5.4M
Biocomputation of the Links Between Muscle Morphology, Coordination and InjuryR01AR056201 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI BLEMKER, SILVIA SALINAS, THELEN, DARRYL G · 2007 to 2010
$1.3M
NIAMS NIH HHS R01 AR056201NIAMS NIH HHS R01AR056201NIBIB NIH HHS R01 EB001763NIBIB NIH HHS R01EB001763
6 · The paper itself

Abstract

Hamstring strain injury is one of the most common injuries in athletes, particularly for sports that involve high speed running. The aims of this study were to determine whether muscle activation and internal morphology influence in vivo muscle behavior and strain injury susceptibility. We measured tissue displacement and strains in the hamstring muscle injured most often, the biceps femoris long head muscle (BFLH), using cine DENSE dynamic magnetic resonance imaging. Strain measurements were used to test whether strain magnitudes are (i) larger during active lengthening than during passive lengthening and (ii) larger for subjects with a relatively narrow proximal aponeurosis than a wide proximal aponeurosis. Displacement color maps showed higher tissue displacement with increasing lateral distance from the proximal aponeurosis for both active lengthening and passive lengthening, and higher tissue displacement for active lengthening than passive lengthening. First principal strain magnitudes were averaged in a 1cm region near the myotendinous junction, where injury is most frequently observed. It was found that strains are significantly larger during active lengthening (0.19 SD 0.09) than passive lengthening (0.13 SD 0.06) (p<0.05), which suggests that elevated localized strains may be a mechanism for increased injury risk during active as opposed to passive lengthening. First principal strains were higher for subjects with a relatively narrow aponeurosis width (0.26 SD 0.15) than wide (0.14 SD 0.04) (p<0.05). This result suggests that athletes who have BFLH muscles with narrow proximal aponeuroses may have an increased risk for BFLH strain injuries.

Indexed as

AthletesModels, BiologicalAdultFemaleHumansMaleMuscle, SkeletalRunningSprains and StrainsTendons

Identifiers

PMID22236527
PMCPMC3695609

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.