Evidence map›Paper›PMID 22235996›Full record

ReviewClinical and experimental immunology2012

Immunology in the clinic review series; focus on cancer: glycolipids as targets for tumour immunotherapy.

L G Durrant, P Noble, I Spendlove

Abstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Increased expression of SSEA-4 on TKI-resistant non-small cell lung cancer with EGFR-T790M mutation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. The Role of Sphingolipids in Cancer Immunotherapy.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Serum sialylation changes in cancer.Glycoconjugate journal · 2018
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

L G DurrantAcademic Department of Clinical Oncology, Molecular Medical Sciences, City Hospital, University of Nottingham, Nottingham, UK. lindy.durrant@nottingham.ac.uk
P Noble
I Spendlove

Funding

Medical Research Council
6 · The paper itself

Abstract

Research into aberrant glycosylation and over-expression of glycolipids on the surface of the majority of cancers, coupled with a knowledge of glycolipids as functional molecules involved in a number of cellular physiological pathways, has provided a novel area of targets for cancer immunotherapy. This has resulted in the development of a number of vaccines and monoclonal antibodies that are showing promising results in recent clinical trials.

Indexed as

AnimalsAntibodies, MonoclonalAntigens, NeoplasmCancer VaccinesCeramidesClinical Trials as TopicGangliosidesGlycolipidsGlycosylationG(M3) GangliosideHumansImmunotherapyLewis Blood Group AntigensMolecular Targeted TherapyNeoplasmsTrisaccharidesAntibodies, MonoclonalAntigens, NeoplasmCancer VaccinesCeramidesgalactosyl-beta(1-3)-N-acetylglucosaminyl-beta(1-3)galactoseGangliosidesGlycolipidsG(M3) GangliosideLewis Blood Group AntigensN-glycolylneuraminyllactosylceramideTrisaccharides

Identifiers

PMID22235996
PMCPMC3278686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.