ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2012
Persistent subretinal fluid after surgery for rhegmatogenous retinal detachment: hypothesis and review.
Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 71 citations in OpenAlex.
- Internal drainage of subretinal fluid during scleral buckling with 27-Gauge wide angle viewing system and flute needle for rhegmatogenous retinal detachment.International ophthalmology · 2025Trial
- Safety and efficacy of subthreshold micropulse yellow laser for persistent subretinal fluid after scleral bucking a randomized clinical trial.Scientific reports · 2024Trial
- Amniotic membrane placement without endotamponade for optic nerve coloboma with extensive serous retinal detachment in papillorenal syndrome: A case report.American journal of ophthalmology case reports · 2025Article
- Optical Coherence Tomography in Retinal Detachment: Prognostic Biomarkers, Surgical Planning, and Postoperative Monitoring.Diagnostics (Basel, Switzerland) · 2025Review
- Subfoveal Choroidal Thickness After Successful Retinal Detachment Repair with Persistent Subretinal Fluid at the Macula.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- The Usefulness of 55° Wide-Field Spectral-Domain Optical Coherence Tomography in Monitoring the Features of Peripheral Subretinal Fluid Remnants after Rhegmatogenous Retinal Detachment Surgery.Diagnostics (Basel, Switzerland) · 2024Article
- Effect of external subretinal fluid drainage on persistent subretinal fluid after scleral buckle surgery in macula-involving rhegmatogenous retinal detachment.Scientific reports · 2023Article
- Characteristics of subretinal particles detected after pars plana vitrectomy for rhegmatogenous retinal detachment.BMC ophthalmology · 2023Article
- Mineralocorticoid receptor antagonists as a potential treatment option in persistent subretinal fluid following the repair of a rhegmatogenous retinal detachment.American journal of ophthalmology case reports · 2023Article
- Inverted multi-layer internal limiting membrane flap for macular hole retinal detachment in high myopia.Scientific reports · 2022Article
- Clinical Analysis of Persistent Subretinal Fluid after Pars Plana Vitrectomy in Macula with Diabetic Tractional Retinal Detachment.Journal of clinical medicine · 2021Article
- Evaluation of the Effects of Silicone Oil on the Macula with Optical Coherence Tomography in Patients with Rhegmatogenous Retinal DetachmentTurkish journal of ophthalmology · 2021Article
- Impact of air injection on subretinal fluid following successful scleral buckling surgery for macular-involving retinal detachment.Scientific reports · 2021Article
- Multifactor analysis of delayed absorption of subretinal fluid after scleral buckling surgery.BMC ophthalmology · 2021Article
- Persistent subretinal fluid following diabetic tractional retinal detachment repair: risk factors, natural history, and management outcomes.International ophthalmology · 2021Article
- Employing Nanostructured Scaffolds to Investigate the Mechanical Properties of Adult Mammalian Retinae Under Tension.International journal of molecular sciences · 2020Article
- Natural history of persistent subretinal fluid following the successful repair of rhegmatogenous retinal detachment.International journal of ophthalmology · 2020Article
- Loculated subretinal fluid after pneumatic vitreolysis.American journal of ophthalmology case reports · 2019Article
- Multiple subretinal fluid blebs after pars plana vitrectomy for rhegmatogenous retinal detachment repair.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Influence of submacular fluid on recovery of retinal function and structure after successful rhegmatogenous retinal reattachment.PloS one · 2019Observational
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPersistent subretinal fluid after rhegmatogenous retinal detachment (RRD) surgery is responsible for delayed recovery, and may affect the final visual outcome. Cause, consequences, and treatment remain elusive.
designLiterature review and case series.
methodsWe reviewed the pathophysiological principles and therapeutic options from the literature, and we report the results from a subretinal fluid cytology study. Nine eyes from nine patients with macula-involving RRD underwent surgical repair. The cellular content of subretinal fluid (SRF) was studied by electron microscopy and anti-rhodopsin immunostaining. All eyes were assessed postoperatively with optical coherence tomography for the detection of persistent submacular fluid (PSF) (Ethics Committee Ghent University Hospital, registration number B6702006169).
resultsCertain patient characteristics as well as surgical methods were implicated. PSF appears to occur more frequently in patients with longstanding detachments treated with buckling surgery. Several therapeutic options have been suggested but safety and efficacy remain unclear. We found PSF in three eyes on postoperative OCT scans, which corresponded to the three cell-rich subretinal samples.
conclusionsPSF after successful RRD repair seems to be related to fluid composition. We hypothesize, in the absence of an effective treatment, that a modified surgical drainage, including a washout of the subretinal space, could evacuate the subretinal fluid more completely, and may prevent this complication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.