ArticleThe American journal of tropical medicine and hygiene2012
Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania.
Article in The American journal of tropical medicine and hygiene, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 8 of them syntheses that pooled it.
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Who cites it
74 citing papers in PubMed, 8 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Viral and host determinants of arboviral disease severity in African populations: A systematic review with meta-analysis.PLoS neglected tropical diseases · 2026Pooled it
- Prevalence of fever of unidentified aetiology in East African adolescents and adults: a systematic review and meta-analysis.Infectious diseases of poverty · 2023Pooled it
- A systematic review and meta-analysis of the aetiological agents of non-malarial febrile illnesses in Africa.PLoS neglected tropical diseases · 2022Pooled it
- Paving the way for human vaccination against Rift Valley fever virus: A systematic literature review of RVFV epidemiology from 1999 to 2021.PLoS neglected tropical diseases · 2022Pooled it
- Dengue Virus Infection and Associated Risk Factors in Africa: A Systematic Review and Meta-Analysis.Viruses · 2021Pooled it
- Pooled it
- Chikungunya fever in Africa: a systematic review.Pathogens and global health · 2020Pooled it
- Events preceding death among chikungunya virus infected patients: a systematic review.Revista da Sociedade Brasileira de Medicina Tropical · 2020Pooled it
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- Lifestyle score is associated with cellular immune profiles in healthy Tanzanian adults.Brain, behavior, & immunity - health · 2024Article
- Spatial Mapping the Dengue and Chikungunya Burden in a Rural Area near Bangalore: a Descriptive Cross-Sectional Study.Journal of arthropod-borne diseases · 2023Article
- Health professionals' knowledge on dengue and health facility preparedness for case detection: A cross-sectional study in Dar es Salaam, Tanzania.PLoS neglected tropical diseases · 2023Article
- Seroprevalence of Dengue and Chikungunya Virus Infections in Children Living in Sub-Saharan Africa: Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2023Review
- Ecological Niche Modeling ofViruses · 2023Article
- Epidemiology and Economic Burden of Chikungunya: A Systematic Literature Review.Tropical medicine and infectious disease · 2023Review
- Seroprevalence of viral and bacterial pathogens among malaria patients in an endemic area of southern Venezuela.Infectious diseases of poverty · 2023Article
- Comparison of RT-qPCR and RT-ddPCR with Rift valley fever virus (RVFV) RNA.Scientific reports · 2023Article
- Incidence of chikungunya virus infections among Kenyan children with neurological disease, 2014-2018: A cohort study.PLoS medicine · 2022Article
- The global burden of Chikungunya fever among children: A systematic literature review and meta-analysis.PLOS global public health · 2022Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
Abstract
Consecutive febrile admissions were enrolled at two hospitals in Moshi, Tanzania. Confirmed acute Chikungunya virus (CHIKV), Dengue virus (DENV), and flavivirus infection were defined as a positive polymerase chain reaction (PCR) result. Presumptive acute DENV infection was defined as a positive anti-DENV immunoglobulin M (IgM) enzyme-linked immunsorbent assay (ELISA) result, and prior flavivirus exposure was defined as a positive anti-DENV IgG ELISA result. Among 870 participants, PCR testing was performed on 700 (80.5%). Of these, 55 (7.9%) had confirmed acute CHIKV infection, whereas no participants had confirmed acute DENV or flavivirus infection. Anti-DENV IgM serologic testing was performed for 747 (85.9%) participants, and of these 71 (9.5%) had presumptive acute DENV infection. Anti-DENV IgG serologic testing was performed for 751 (86.3%) participants, and of these 80 (10.7%) had prior flavivirus exposure. CHIKV infection was more common among infants and children than adults and adolescents (odds ratio [OR] 1.9, P = 0.026) and among HIV-infected patients with severe immunosuppression (OR 10.5, P = 0.007). CHIKV infection is an important but unrecognized cause of febrile illness in northern Tanzania. DENV or other closely related flaviviruses are likely also circulating.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.