Evidence map›Paper›PMID 22232373›Full record

ReviewClinical microbiology reviews2012

The Malassezia genus in skin and systemic diseases.

Georgios Gaitanis, Prokopios Magiatis, Markus Hantschke, Ioannis D Bassukas, Aristea Velegraki

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 253 papers.

0numbers the graph read from it
0cells of the map it votes in
253citing papers in PubMed
27.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05476731 unknown statusnot on this mapstarted 2022, after this paper: background citation

Phenotypic and Genotypic Characterization of Malassezia Species Isolated From Malassezia Associated Skin Diseases

TypeobservationalSponsorSohag UniversityRan2022 to 2023Enrolled100ConditionsMalassezia InfectionArmsculture and antifungal sensitivity and molecular detection
NCT07433907 nacompletednot on this mapstarted 2026, after this paper: background citation

A Prospective, Randomized, Split-Face Pilot Study Comparing the Efficacy of the Institute of Dermatology's Antioxidant Moisturizing Serum in Mild to Moderate Seborrheic Dermatitis

TypeinterventionalSponsorInstitute of Dermatology, ThailandRan2026 to 2026Enrolled13ConditionsSeborrheic Dermatitis on the FaceArmsAntioxidant moisturizing serum
3 · Its place in the literature

Who cites it

253 citing papers in PubMed, 634 citations in OpenAlex.

  1. First case of neonatal bloodstream infection caused byExperimental and therapeutic medicine · 2026
    Article
  2. Article
  3. Review
  4. Host skin lipids triggerbioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Shared occurrence ofOne health (Amsterdam, Netherlands) · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Microbiome dysbiosis and therapeutic restoration in atopic dermatitis.Frontiers in cellular and infection microbiology · 2026
    Review
  18. Article
  19. Article
  20. Extracellular vesicles produced byExtracellular vesicles and circulating nucleic acids · 2026
    Review

193 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Georgios GaitanisDepartment of Skin and Venereal Diseases, University of Ioannina Medical School, Greece. ggaitan@cc.uoi.gr
Prokopios Magiatis
Markus Hantschke
Ioannis D Bassukas
Aristea Velegraki
National and Kapodistrian University of Athens · GRUniversity of Ioannina · GRDermatopathologie Friedrichshafen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last 15 years, the genus Malassezia has been a topic of intense basic research on taxonomy, physiology, biochemistry, ecology, immunology, and metabolomics. Currently, the genus encompasses 14 species. The 1996 revision of the genus resulted in seven accepted taxa: M. furfur, M. pachydermatis, M. sympodialis, M. globosa, M. obtusa, M. restricta, and M. slooffiae. In the last decade, seven new taxa isolated from healthy and lesional human and animal skin have been accepted: M. dermatis, M. japonica, M. yamatoensis, M. nana, M. caprae, M. equina, and M. cuniculi. However, forthcoming multidisciplinary research is expected to show the etiopathological relationships between these new species and skin diseases. Hitherto, basic and clinical research has established etiological links between Malassezia yeasts, pityriasis versicolor, and sepsis of neonates and immunocompromised individuals. Their role in aggravating seborrheic dermatitis, dandruff, folliculitis, and onychomycosis, though often supported by histopathological evidence and favorable antifungal therapeutic outcomes, remains under investigation. A close association between skin and Malassezia IgE binding allergens in atopic eczema has been shown, while laboratory data support a role in psoriasis exacerbations. Finally, metabolomic research resulted in the proposal of a hypothesis on the contribution of Malassezia-synthesized aryl hydrocarbon receptor (AhR) ligands to basal cell carcinoma through UV radiation-induced carcinogenesis.

Indexed as

HumansMalasseziaMycoses

Identifiers

PMID22232373
PMCPMC3255962
OpenAlexW2147563741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.