ReviewTranscription
The unexpected traits associated with core promoter elements.
Review in Transcription. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- A Functional SNP in the Promoter Region of Ovine IDO2 Associated With Melatonin Levels via Affecting Transcription Activity by CLOCK.Animal genetics · 2026Article
- Application of genome editing techniques to regulate gene expression in crops.BMC plant biology · 2024Review
- Computational identification and experimental characterization of preferred downstream positions in human core promoters.PLoS computational biology · 2021Article
- Episodes of Rapid Recovery of the Functional Activity of theFrontiers in genetics · 2021Article
- Article
- The Core Promoter Is a Regulatory Hub for Developmental Gene Expression.Frontiers in cell and developmental biology · 2021Review
- Archaeal transcription.Transcription · 2020Review
- So close, no matter how far: multiple paths connecting transcription to mRNA translation in eukaryotes.EMBO reports · 2020Review
- An Epigenetic Journey: Epstein-Barr Virus Transcribes Chromatinized and Subsequently Unchromatinized Templates during Its Lytic Cycle.Journal of virology · 2019Review
- Article
- Environmental Stress Responses ofFrontiers in genetics · 2018Article
- DTIE, a novel core promoter element that directs start site selection in TATA-less genes.Nucleic acids research · 2016Article
- Sp1 upregulates the proximal promoter activity of the mouse collagen α1(XI) gene (Col11a1) in chondrocytes.In vitro cellular & developmental biology. Animal · 2016Article
- Structure-Function Analysis of the Drosophila melanogaster Caudal Transcription Factor Provides Insights into Core Promoter-preferential Activation.The Journal of biological chemistry · 2015Article
- The distal upstream promoter in Ly49 genes, Pro1, is active in mature NK cells and T cells, does not require TATA boxes, and displays enhancer activity.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- ElemeNT: a computational tool for detecting core promoter elements.Transcription · 2015Article
- Co-occurrence of transcription and translation gene regulatory features underlies coordinated mRNA and protein synthesis.BMC genomics · 2014Article
- Core promoter functions in the regulation of gene expression of Drosophila dorsal target genes.The Journal of biological chemistry · 2014Article
- A novel, non-radioactive eukaryotic in vitro transcription assay for sensitive quantification of RNA polymerase II activity.BMC molecular biology · 2014Article
- RNA polymerase II pausing during development.Development (Cambridge, England) · 2014Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The core promoter of eukaryotic coding and non-coding genes that are transcribed by RNA polymerase II (RNAP II) is composed of DNA elements surrounding the transcription start site. These elements serve as the docking site of the basal transcription machinery and have an important role in determining the position and directing the rate of transcription initiation. This review summarizes the current knowledge about core promoter elements and focuses on several unexpected links between core promoter structure and certain gene features. These include the association between the presence or absence of a TATA-box and gene length, gene structure, gene function, evolution rate and transcription elongation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.