Trial reportLangenbeck's archives of surgery2012
The safety of energy-based devices in open thyroidectomy: a prospective, randomised study comparing the LigaSure™ (LF1212) and the Harmonic® FOCUS.
Trial report in Langenbeck's archives of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- ENERgized vessel sealing systems versus CONventional hemostasis techniques in thyroid surgery--the ENERCON systematic review and network meta-analysis.Langenbeck's archives of surgery · 2013Pooled it
- Sutureless thyroidectomy with energy-based devices: Cerrahpasa experience.Updates in surgery · 2013Trial
- Association Between Collagen-Based Hemostatic Patch Use and Patient-Reported Recovery After Bilateral Thyroidectomy: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Intraoperative Neuromonitoring Does Not Reduce the Risk of Temporary and Definitive Recurrent Laryngeal Nerve Damage during Thyroid Surgery: A Systematic Review and Meta-Analysis of Endoscopic Findings from 73,325 Nerves at Risk.Journal of personalized medicine · 2023Review
- The Use of Harmonic Focus and Thunderbeat Open Fine Jaw in Thyroid Surgery: Experience of a High-Volume Center.Journal of clinical medicine · 2022Article
- Safety Parameters of Quantum Molecular Resonance Devices During Thyroid Surgery: Porcine Model Using Continuous Neuromonitoring.Frontiers in endocrinology · 2022Article
- Thyroidectomy with energy-based devices: surgical outcomes and complications-comparison between Harmonic Focus, LigaSure Small Jaw and Thunderbeat Open Fine Jaw.Gland surgery · 2020Article
- Safety of Ligasure exact dissector in thyroidectomy with continuous neuromonitoring: a porcine model.Gland surgery · 2020Article
- Energy-based devices for hemostasis in thyroid surgery.Gland surgery · 2020Review
- Reply to the commentary by Dr. Sauerland S. and Dr. Gross CTR.Langenbeck's archives of surgery · 2019Article
- Questions on randomised trials by Dionigi and coworkers.Langenbeck's archives of surgery · 2019Article
- Prevention and management of bleeding in thyroid surgery.Gland surgery · 2017Review
- Thyroidectomy in elderly patients aged ≥70 years.Gland surgery · 2017Review
- A comparison of surgical outcomes and complications between hemostatic devices for thyroid surgery: a network meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Review
- Article
- Safety of energy based devices for hemostasis in thyroid surgery.Gland surgery · 2016Review
- Indocyanine green-enhanced fluorescence for assessing parathyroid perfusion during thyroidectomy.Gland surgery · 2016Review
- Comparison of the harmonic focus and the thunderbeat for open thyroidectomy.Langenbeck's archives of surgery · 2016Article
- Harmonic versus LigaSure hemostasis technique in thyroid surgery: A meta-analysis.Biomedical reports · 2016Article
- Is sutureless thyroid surgery safe in the hands of surgical trainees. A single centre retrospective study.BMC research notes · 2016Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe options for haemostasis and dissection during modern thyroid surgery include the use of a bipolar vessel sealing system and ultrasonic technology. The aim of this study was to compare these energy-based devices (EBDs) with respect to their use in open thyroidectomy.
methodsThe FOCUS Shear (F) and LigaSure LF1212 (L) were evaluated. A total of 182 consecutive patients scheduled for open thyroidectomy were prospectively randomised into two similarly sized groups. The parameters of operative time, morbidity, incision length, postoperative pain and hospital stay were analysed.
resultsThe main clinically primary endpoints of the two devices were identical in the study as the rate of nerve lesions, bleeding, drainage, operative time and postoperative calcium concentration with no significant differences with respect to the instrument utilised. The mean length of the incision was greater in the F group (p < 0.05). Patients in the F group were more likely to complain of pain while swallowing (p < 0.001). Early postoperative measurements of intact parathyroid hormone plasma levels revealed that although the levels were within the reference range, they were significantly lower in the F group (p < 0.001). Oral calcium supplementation was significantly higher and more prolonged in the F group.
conclusionsThe present study demonstrated no significant difference in the rates of postoperative morbidity associated with these two different EBDs used. Differences in clinically less significant were founded and focused on.
Indexed as
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22230963What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.