Evidence map›Paper›PMID 22229863›Full record

ArticleAntioxidants & redox signaling2012

Is elevated gastric tissue NOX2 associated with lymphoma of mucosa-associated lymphoid tissue?

Emilie Bessède, Christiane Copie-Bergman, Philippe Lehours, Michael Levy, Karen Leroy, Maryse Baia, Audrey Riou, Francis Mégraud, Jean-Charles Delchier, Nathalie Salles

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants & redox signaling, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Clinical aspects of malt lymphomas.Current hematologic malignancy reports · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Emilie BessèdeINSERM U853, Bordeaux, France.
Christiane Copie-Bergman
Philippe Lehours
Michael Levy
Karen Leroy
Maryse Baia
Audrey Riou
Francis Mégraud
Jean-Charles Delchier
Nathalie Salles
Inserm · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abstract Helicobacter pylori infection plays a crucial role in the pathogenesis of gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT). However, the host response to this infection is also important in the development of the disease. In particular, NADPH oxidases (NOXs) which generate reactive oxygen species are known to induce cell damage possibly leading to carcinogenesis. We analyze for the first time NOX expression in a series of well characterized gastric MALT lymphoma (GML) patients in comparison with controls. Our observation leads to the hypothesis that NOX2 expression is significantly associated with GML.

Indexed as

AdultAgedAged, 80 and overChromosomes, Human, Pair 11Chromosomes, Human, Pair 18FemaleHumansImmunohistochemistryLymphoma, B-Cell, Marginal ZoneMaleMembrane GlycoproteinsMiddle AgedNADPH Oxidase 2NADPH OxidasesReactive Oxygen SpeciesReal-Time Polymerase Chain ReactionCYBB protein, humanMembrane GlycoproteinsNADPH Oxidase 2NADPH OxidasesReactive Oxygen Species

Identifiers

PMID22229863
PMCPMC3474711
OpenAlexW2051608852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.