ArticleAnalytical chemistry2012
Simultaneous on-chip DC dielectrophoretic cell separation and quantitative separation performance characterization.
Article in Analytical chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 46 citations in OpenAlex.
- ZnO Nanowire-Anchored Microfluidic Device With Herringbone Structure Fabricated by Maskless Photolithography.Biomedical engineering and computational biology · 2020Article
- A review of polystyrene bead manipulation by dielectrophoresis.RSC advances · 2019Review
- Integrated Microfluidic Device for Enrichment and Identification of Circulating Tumor Cells from the Blood of Patients with Colorectal Cancer.Disease markers · 2019Article
- Hydrodynamics in Cell Studies.Chemical reviews · 2018Review
- A high-throughput acoustic cell sorter.Lab on a chip · 2015Article
- Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation.Lab on a chip · 2015Review
- Cell separation using tilted-angle standing surface acoustic waves.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Quantifying the volume of single cells continuously using a microfluidic pressure-driven trap with media exchange.Biomicrofluidics · 2014Article
- Recent advances in microfluidic cell separations.The Analyst · 2013Review
- Size-based hydrodynamic rare tumor cell separation in curved microfluidic channels.Biomicrofluidics · 2013Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Through integration of a MOSFET-based microfluidic Coulter counter with a dc-dielectrophoretic cell sorter, we demonstrate simultaneous on-chip cell separation and sizing with three different samples including 1) binary mixtures of polystyrene beads, 2) yeast cells of continuous size distribution, and 3) mixtures of 4T1 tumor cells and murine bone marrow cells. For cells with continuous size distribution, it is found that the receiver operator characteristic analysis is an ideal method to characterize the separation performance. The characterization results indicate that dc-DEP separation performance degrades as the sorting throughput (cell sorting rate) increases, which provides insights into the design and operation of size-based microfluidic cell separation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.