Evidence map›Paper›PMID 22229107›Full record

ArticleFemale pelvic medicine & reconstructive surgery2010

Long-Term Outcomes of the Total or Supracervical Hysterectomy (TOSH) Trial.

W Jerod Greer, Holly E Richter, Thomas L Wheeler, R Edward Varner, Jeff M Szychowski, Miriam Kuppermann, Lee A Learman

Abstract read
In one paragraph

Article in Female pelvic medicine & reconstructive surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. The Effects of Hysterectomy on Urinary and Sexual Functions of Women with Cervical Cancer: A Systematic Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Patient Perceptions of Planned Organ Removal During Hysterectomy.Journal of patient-centered research and reviews · 2019
    Article
  8. Article
  9. A Simple Approach to Specimen Retrieval via Posterior Colpotomy Incision.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

W Jerod GreerDepartment of Obstetrics & Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.
Holly E Richter
Thomas L Wheeler
R Edward Varner
Jeff M Szychowski
Miriam Kuppermann
Lee A Learman
University of Alabama at Birmingham · US

Funding

Mid Career Award in Patient Oriented Pelvic Floor ResearchK24DK068389 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RICHTER, HOLLY E · 2005 to 2014
$1.7M
Intermediate Outcomes of Hysterectomy and AlternativesR01HS011657 · AHRQ · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUPPERMANN, MIRIAM · 2002 to 2006
$512k
MEDICINE OR SURGERY?(MS?)U01HS009478 · AHRQ · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI HULLEY, STEPHEN B. · 1996 to 2000
–
AHRQ HHS R01 HS011657AHRQ HHS U01 HS009478NIDDK NIH HHS K24 DK068389
6 · The paper itself

Abstract

backgroundParticipants in the multi-center, randomized Total or Supracervical Hysterectomy (TOSH) trial showed within-group improvement in pelvic floor symptoms 2 years post-surgery and no differences between supracervical (SCH) versus total hysterectomy (TAH). This study describes longer term outcomes from the largest recruiting site. STUDY

designQuestionnaires addressing pelvic symptoms, sexual function, and health-related quality of life were administered. Linear models and McNemar's test were utilized.

resultsThirty-seven participants (69%) responded (19 TAH, 18 SCH); mean follow up was 9.1±0.7 years. No between-group differences emerged in urinary incontinence, voiding dysfunction, pelvic prolapse symptoms and overall health related quality of life (HRQOL). Within-group analysis showed significant improvement in the ability to have and enjoy sex (P = 0.002) and in the SF-36 physical component summary score (P = 0.03) among women randomized to TAH.

conclusion9 years after surgery, TOSH participants continue to experience improvement and show no major between-group differences in lower urinary tract or pelvic floor symptoms conferring no major benefit of SCH over TAH.

Identifiers

PMID22229107
PMCPMC3252027
OpenAlexW2056177749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.