ArticleInternational journal of hepatology2011
Prevention and management of bacterial infections in cirrhosis.
Article in International journal of hepatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Impact of bacterial infection on native liver survival in children with cirrhosis due to biliary atresia.Clinical and experimental pediatrics · 2026Article
- Article
- Microbiome alterations are related to an imbalance of immune response and bacterial translocation in BDL-rats.Iranian journal of basic medical sciences · 2020Article
- Bacterial Infections in Patients with Liver Cirrhosis in an Internal Medicine Department.GE Portuguese journal of gastroenterology · 2019Article
- Acute-on-chronic liver failure: Objective admission and support criteria in the intensive care unit.JHEP reports : innovation in hepatology · 2019Review
- Risk factors predicting nosocomial, healthcare-associated and community-acquired infection in spontaneous bacterial peritonitis and survival outcome.Clinical and experimental hepatology · 2019Article
- Hepatic Encephalopathy in Patients in Lviv (Ukraine).Journal of translational internal medicine · 2018Article
- Impact of transjugular intrahepatic portosystemic shunt on post-colectomy complications in patients with ulcerative colitis and primary sclerosing cholangitis.Gastroenterology report · 2015Article
- Thoracic perspective revisited in chronic liver disease.Gastroenterology report · 2015Review
- A multicenter prospective study of infections related morbidity and mortality in cirrhosis of liver.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2014Article
- Diagnosis and management of bacterial infections in decompensated cirrhosis.World journal of hepatology · 2013Article
- The role of serum procalcitonin levels in predicting ascitic fluid infection in hospitalized cirrhotic and non-cirrhotic patients.International journal of medical sciences · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with cirrhosis of liver are at risk of developing serious bacterial infections due to altered immune defenses. Despite the widespread use of broad spectrum antibiotics, bacterial infection is responsible for up to a quarter of the deaths of patients with liver disease. Cirrhotic patients with gastrointestinal bleed have a considerably higher incidence of bacterial infections particularly spontaneous bacterial peritonitis. High index of suspicion is required to identify infections at an early stage in the absence of classical signs and symptoms. Energetic use of antibacterial treatment and supportive care has decreased the morbidity and mortality over the years; however, use of antibiotics has to be judicious, as their indiscriminate use can lead to antibiotic resistance with potentially disastrous consequences. Preventive strategies are still in evolution and involve use of antibiotic prophylaxis in patients with gastrointestinal bleeding and spontaneous bacterial infections and selective decontamination of the gut and oropharynx.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.