ArticlePloS one2011
A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 63 citations in OpenAlex.
- Intracellular microbial shifts during COVID-19 infection and longitudinal recovery revealed by single-cell RNA sequencing.iScience · 2026Article
- Comparative genomics of the primary endosymbiont Buchnera aphidicola in aphid hosts and their coevolutionary relationships.BMC biology · 2024Article
- Comparative Transcriptomics of Fat Bodies between Symbiotic and Quasi-Aposymbiotic Adult Females ofInternational journal of molecular sciences · 2024Article
- Proteolytic Activity of DegP Is Required for theMicrobiology spectrum · 2023Article
- A complex interplay of evolutionary forces continues to shape ancient co-occurring symbiont genomes.iScience · 2022Article
- Adaptive Variation ofACS omega · 2021Article
- Host-Endosymbiont Genome Integration in a Deep-Sea Chemosymbiotic Clam.Molecular biology and evolution · 2021Article
- At the Gate of Mutualism: Identification of Genomic Traits Predisposing to Insect-Bacterial Symbiosis in Pathogenic Strains of the Aphid SymbiontFrontiers in cellular and infection microbiology · 2021Article
- Isolation of the Buchnera aphidicola flagellum basal body complexes from the Buchnera membrane.PloS one · 2021Article
- Insect-Symbiont Gene Expression in the Midgut Bacteriocytes of a Blood-Sucking Parasite.Genome biology and evolution · 2020Article
- Coordination of host and symbiont gene expression reveals a metabolic tug-of-war between aphids andProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Trading amino acids at the aphid-Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Single-cell genomics unveiled a cryptic cyanobacterial lineage with a worldwide distribution hidden by a dinoflagellate host.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Antimicrobial activity and carbohydrate metabolism in the bacterial metagenome of the soil-living invertebrate Folsomia candida.Scientific reports · 2019Article
- Evolution of host support for two ancient bacterial symbionts with differentially degraded genomes in a leafhopper host.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Article
- Predictive Genomic Analyses Inform the Basis for Vitamin Metabolism and Provisioning in Bacteria-Arthropod Endosymbioses.G3 (Bethesda, Md.) · 2017Article
- Determinism and Contingency Shape Metabolic Complementation in an Endosymbiotic Consortium.Frontiers in microbiology · 2017Article
- Metabolic Complementation in Bacterial Communities: Necessary Conditions and Optimality.Frontiers in microbiology · 2016Article
- A metagenomic approach from aphid's hemolymph sheds light on the potential roles of co-existing endosymbionts.Microbiome · 2015Article
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
Buchnera aphidicola is an obligate symbiotic bacterium that sustains the physiology of aphids by complementing their exclusive phloem sap diet. In this study, we reappraised the transport function of different Buchnera strains, from the aphids Acyrthosiphon pisum, Schizaphis graminum, Baizongia pistaciae and Cinara cedri, using the re-annotation of their transmembrane proteins coupled with an exploration of their metabolic networks. Although metabolic analyses revealed high interdependencies between the host and the bacteria, we demonstrate here that transport in Buchnera is assured by low transporter diversity, when compared to free-living bacteria, being mostly based on a few general transporters, some of which probably have lost their substrate specificity. Moreover, in the four strains studied, an astonishing lack of inner-membrane importers was observed. In Buchnera, the transport function has been shaped by the distinct selective constraints occurring in the Aphididae lineages. Buchnera from A. pisum and S. graminum have a three-membraned system and similar sets of transporters corresponding to most compound classes. Transmission electronic microscopic observations and confocal microscopic analysis of intracellular pH fields revealed that Buchnera does not show any of the typical structures and properties observed in integrated organelles. Buchnera from B. pistaciae seem to possess a unique double membrane system and has, accordingly, lost all of its outer-membrane integral proteins. Lastly, Buchnera from C. cedri revealed an extremely poor repertoire of transporters, with almost no ATP-driven active transport left, despite the clear persistence of the ancestral three-membraned system.
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