ArticleFuture neurology2011
Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain.
Article in Future neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 3 syntheses or guidelines pooled it, 191 citations in OpenAlex.
- Totality of the Evidence Suggests Prenatal Cannabis Exposure Does Not Lead to Cognitive Impairments: A Systematic and Critical Review.Frontiers in psychology · 2020Pooled it
- Effects of prenatal marijuana exposure on neuropsychological outcomes in children aged 1-11 years: A systematic review.Paediatric and perinatal epidemiology · 2018Pooled it
- Risks associated with the non-medicinal use of cannabis.Deutsches Arzteblatt international · 2015Pooled it
- The Role of Acculturation and Alcohol Problems on Frequency of Cannabis Use Among Latinas at Risk of an Alcohol-Exposed Pregnancy.Substance use & misuse · 2019Trial
- Preventing Alcohol and Tobacco Exposed Pregnancies: CHOICES Plus in Primary Care.American journal of preventive medicine · 2017Trial
- Prenatal THC Exposure Differentially Alters Gut Physiology and Microbiota in Stress-Resilient and Vulnerable Mice.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Medical Cannabis During Pregnancy and Breastfeeding: Is the Concern Fully Evidence-Based?Biomedicines · 2026Article
- Before Birth, Beyond Childhood: Understanding the Influence of Prenatal Substance Exposure on Psychiatric Diagnoses.medRxiv : the preprint server for health sciences · 2026Article
- Cannabis use, preterm birth, and small for gestational age: findings from the national birth defects prevention study.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- New approach to document cannabis toxicity during pregnancy: a low abundance molecular species detection in long-term formalin-fixed paraffin embedded fetal tissues. A technological report.International journal of legal medicine · 2026Article
- Prenatal and Postnatal Exposure to Tobacco and Cannabis and Child Aggression at Early School Age: Role of Early Maternal Sensitivity.Child psychiatry and human development · 2026Article
- The changing landscape of cannabis use: impact on maternal health and neonatal outcomes.Pediatric research · 2026Review
- Prenatal Cannabis Exposure Shaping Altered Brain Connectivity: Neural Correlates of Cognitive and Mental Health Variability in Offspring.Research square · 2026Article
- Altered Neurobehavioral Reward Response Predicts Psychotic-Like Experiences in Youth Exposed to Cannabis Prenatally.Biological psychiatry · 2026Article
- Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study.Molecular psychiatry · 2026Article
- Activation of cannabinoid receptor CB1 leads to aberrant myelination in development.bioRxiv : the preprint server for biology · 2025Article
- Environmental Exposures Influence Fetal Brain Growth and Risk of Neonatal Brain Injury in Congenital Heart Disease.Research square · 2025Article
- Research Review: What we have learned about the endocannabinoid system in developmental psychopathology.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- A systematic review investigating prenatal cannabis and tobacco co-exposure: Impacts on neonatal, behavioral, cognitive and physiological outcomes.Drug and alcohol dependence reports · 2025Review
- Tobacco and cannabis use among pregnant women with prenatal opioid use.Addictive behaviors · 2025Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Cannabis is the most commonly used illicit substance among pregnant women. Human epidemiological and animal studies have found that prenatal cannabis exposure influences brain development and can have long-lasting impacts on cognitive functions. Exploration of the therapeutic potential of cannabis-based medicines and synthetic cannabinoid compounds has given us much insight into the physiological roles of endogenous ligands (endocannabinoids) and their receptors. In this article, we examine human longitudinal cohort studies that document the long-term influence of prenatal exposure to cannabis, followed by an overview of the molecular composition of the endocannabinoid system and the temporal and spatial changes in their expression during brain development. How endocannabinoid signaling modulates fundamental developmental processes such as cell proliferation, neurogenesis, migration and axonal pathfinding are also summarized.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.