ArticleEuropean journal of dentistry2012
Development of an intracanal mature Enterococcus faecalis biofilm and its susceptibility to some antimicrobial intracanal medications; an in vitro study.
Article in European journal of dentistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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Who cites it
29 citing papers in PubMed, 86 citations in OpenAlex.
- The antibacterial effect and the incidence of post-operative pain after the application of nano-based intracanal medications during endodontic retreatment: a randomized controlled clinical trial.Clinical oral investigations · 2022Trial
- Arginine-loaded silica nanoparticles inhibit E. faecalis in root canals.Journal of materials science. Materials in medicine · 2026Article
- Synergistic antibiofilm activity of methylene blue and silver nanoparticle-mediated photothermal therapy against Enterococcus faecalis biofilm.Scientific reports · 2025Article
- Cytocompatibility, Antibacterial, and Anti-Biofilm Efficacy of Grape Seed Extract and Quercetin Hydrogels Against a Mature Endodontic Biofilm Ex Vivo Model.Journal of clinical medicine · 2024Article
- Effect of Herbal Extract ofInternational journal of clinical pediatric dentistry · 2024Article
- Antibacterial biofilm efficacy of calcium hydroxide loaded on Gum Arabic nanocarrier: an in-vitro study.BMC oral health · 2024Article
- Silver Nanoparticles as an Intracanal Medicament: A Scoping Review.TheScientificWorldJournal · 2023Article
- Review
- Antibacterial effectiveness of diluted preparations of intracanal medicaments used in regenerative endodontic treatment on dentin infected by bacterial biofilm: AnDental research journal · 2021Article
- Preparation of PLGA-chitosan based nanocarriers for enhancing antibacterial effect of ciprofloxacin in root canal infection.Drug delivery · 2020Article
- Formulation and characterization of chlorhexidine HCl nanoemulsion as a promising antibacterial root canal irrigant: in-vitro and ex-vivo studies.International journal of nanomedicine · 2019Article
- Comparison of Antimicrobial Effects of Triple Antibiotic Paste and Calcium Hydroxide Mixed with 2% Chlorhexidine as Intracanal Medicaments Against Enterococcus faecalis Biofilm.Journal of dentistry (Tehran, Iran) · 2018Article
- The acid tolerance response and pH adaptation ofF1000Research · 2018Article
- Minimum Intracanal Dressing Time of Triple Antibiotic Paste to Eliminate Enterococcus Faecalis (ATCC 29212) and Determination of Minimum Inhibitory Concentration and Minimum Bactericidal Concentration: An Ex Vivo Study.Journal of dentistry (Tehran, Iran) · 2018Article
- Article
- Comparative Evaluation of Anti Microbial effects of Triple Antibiotic Paste and Amox and its derivatives againstJournal of clinical and experimental dentistry · 2017Article
- Chitosan-propolis nanoparticle formulation demonstrates anti-bacterial activity against Enterococcus faecalis biofilms.PloS one · 2017Article
- Antibacterial TAP-mimic electrospun polymer scaffold: effects on P. gingivalis-infected dentin biofilm.Clinical oral investigations · 2016Article
- Phage therapy against Enterococcus faecalis in dental root canals.Journal of oral microbiology · 2016Review
- Evaluation of Antimicrobial Effects of Different Concentrations of Triple Antibiotic Paste on Mature Biofilm of Enterococcus faecalis.Journal of dental research, dental clinics, dental prospects · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo develop a mature biofilm of Enterococcus faecalis inside the root canal system and to test its susceptibility to some antimicrobial medications in vitro.
methodsSingle rooted premolars were mechanically enlarged, sterilized, and then infected with a clinical isolate of E. faecalis. Biofilm formation and maturation was monitored using SEM. Biofilm bacteria were exposed to Amoxicillin+clavulanate, Ciprofloxacin, Clindamycin, Doxycycline, and calcium hydroxide as intracanal medications for 1 week. Finally bacterial samples were collected, and colony-forming units were enumerated.
resultsSEM examination confirmed the formation of a mature biofilm at the end of the incubation period. All the chemotherapeutic agents used were significantly better than Calcium hydroxide in elimination of biofilm bacteria. The antimicrobial effect of Amoxicillin + clavulanate, Ciprofloxacin and Clindamycin was significantly better than Doxycycline (P=.05). However the difference in the antimicrobial effectiveness among them was statistically non-significant (P=.05).
conclusionsThe method used for bacterial biofilm development and maturation is reliable and can be used to assess the anti bacterial potential of endodontic materials. Also, the local application of antibacterial agents can be beneficial in resistant cases of apical periodontitis but only after careful culture and sensitivity testing to choose the appropriate agent for the existing flora.
Indexed as
Identifiers
22229006PMC3252799W194390998What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.