Evidence map›Paper›PMID 22228996›Full record

ReviewInternational journal of nanomedicine2011

Nanomedicine as an emerging approach against intracellular pathogens.

Andrea L Armstead, Bingyun Li

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Review
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  6. In vitro efficacy of polymer coated miltefosine drug against leishmania tropica.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
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  14. Impact of industry 4.0 to create advancements in orthopaedics.Journal of clinical orthopaedics and trauma · 2020
    Article
  15. Multi-functionalized nanocarriers targeting bacterial reservoirs to overcome challenges of multi drug-resistance.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2020
    Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrea L ArmsteadBiomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopedics, School of Medicine, West Virginia University, Morgantown, WV 26506-9196, USA.
Bingyun Li

Funding

WC-Co nanoparticles in initiating angiogenesis by reactive oxygen speciesR01HL091456 · NHLBI · WEST VIRGINIA UNIVERSITY · PI JIANG, BINGHUA · 2009 to 2010
$832k
NHLBI NIH HHS HL091456NHLBI NIH HHS R01 HL091456
6 · The paper itself

Abstract

Diseases such as tuberculosis, hepatitis, and HIV/AIDS are caused by intracellular pathogens and are a major burden to the global medical community. Conventional treatments for these diseases typically consist of long-term therapy with a combination of drugs, which may lead to side effects and contribute to low patient compliance. The pathogens reside within intracellular compartments of the cell, which provide additional barriers to effective treatment. Therefore, there is a need for improved and more effective therapies for such intracellular diseases. This review will summarize, for the first time, the intracellular compartments in which pathogens can reside and discuss how nanomedicine has the potential to improve intracellular disease therapy by offering properties such as targeting, sustained drug release, and drug delivery to the pathogen's intracellular location. The characteristics of nanomedicine may prove advantageous in developing improved or alternative therapies for intracellular diseases.

Indexed as

AnimalsAnti-Infective AgentsCommunicable DiseasesHumansNanocapsulesNanomedicineAnti-Infective AgentsNanocapsulesdrug deliveryinfectionintracellular pathogennanomedicinenanoparticle

Identifiers

PMID22228996
PMCPMC3252676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.