Evidence map›Paper›PMID 22228975›Full record

ArticleWorld journal of gastroenterology2012

Unsuccessful treatment of four patients with acute graft-vs-host disease after liver transplantation.

Xiao-Bo Chen, Jie Yang, Ming-Qing Xu, Tian-Fu Wen, Lu-Nan Yan

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiao-Bo ChenDepartment of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Jie Yang
Ming-Qing Xu
Tian-Fu Wen
Lu-Nan Yan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate appropriate therapeutic strategies for graft-vs-host disease (GVHD) following liver transplantation.

methodsFour patients who developed GVHD after liver transplantation in West China Hospital were included in this study. Therapeutic strategies with augmentation or withdrawal of immunosuppressants combined with supportive therapy were investigated in these patients. In addition, a literature review of patients who developed GVHD after liver transplantation was performed.

resultsAlthough a transient response to initial treatment was detected, all four patients died of complications from GVHD: one from sepsis with multiple organ failure, one from gastrointestinal bleeding, and the other two from sepsis with gastrointestinal bleeding. Few consensuses for the treatment of GVHD after liver transplantation have been reached.

conclusionNew and effective treatments are required for GVHD after liver transplantation to improve the prognosis of patients with this diagnosis.

Indexed as

AdultFemaleGraft vs Host DiseaseHumansImmunosuppressive AgentsLiver TransplantationMaleMiddle AgedPostoperative ComplicationsPrognosisTreatment OutcomeImmunosuppressive AgentsGraft-vs-host diseaseImmunosuppressantImmunosuppressionLiver transplantationTreatment

Identifiers

PMID22228975
PMCPMC3251810

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.