Evidence map›Paper›PMID 22228951›Full record

ArticlePharmacognosy reviews2010

Free radicals, antioxidants and functional foods: Impact on human health.

V Lobo, A Patil, A Phatak, N Chandra

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Pharmacognosy reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1,483 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,483citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04046432 nacompletednot on this mapstarted 2017, after this paper: background citation

Effects of Vigiis 101-LAB on Gut Health

TypeinterventionalSponsorSunWay Biotech Co., LTD.Ran2017 to 2018Enrolled54ConditionsGastrointestinal MicrobiomeArmsVigiis 101-LAB, Placebo
NCT04088474 nacompletednot on this mapstarted 2016, after this paper: background citation

Functional Assessment in The Intestinal Flora Improvement

TypeinterventionalSponsorSunWay Biotech Co., LTD.Ran2016 to 2016Enrolled36ConditionsGastrointestinal MicrobiomeArmsVigiis 101-LAB, Placebo
3 · Its place in the literature

Who cites it

1,483 citing papers in PubMed, 1 synthesis or guideline pooled it, 5,345 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Theoretical studies to understand theJournal of molecular modeling · 2026
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  10. Review
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  14. Article
  15. Altered Distribution of CD14American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Article
  16. Article
  17. Review
  18. Food science & nutrition · 2026
    Article
  19. Article
  20. Article

1,423 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

V LoboDepartment of Botany, Birla College, Kalyan - 421 304, Maharastra, India .
A Patil
A Phatak
N Chandra
Maharaja Bir Bikram University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, there has been a great deal of attention toward the field of free radical chemistry. Free radicals reactive oxygen species and reactive nitrogen species are generated by our body by various endogenous systems, exposure to different physiochemical conditions or pathological states. A balance between free radicals and antioxidants is necessary for proper physiological function. If free radicals overwhelm the body's ability to regulate them, a condition known as oxidative stress ensues. Free radicals thus adversely alter lipids, proteins, and DNA and trigger a number of human diseases. Hence application of external source of antioxidants can assist in coping this oxidative stress. Synthetic antioxidants such as butylated hydroxytoluene and butylated hydroxyanisole have recently been reported to be dangerous for human health. Thus, the search for effective, nontoxic natural compounds with antioxidative activity has been intensified in recent years. The present review provides a brief overview on oxidative stress mediated cellular damages and role of dietary antioxidants as functional foods in the management of human diseases.

Indexed as

Ageingantioxidantfree radicalsoxidative stress

Identifiers

PMID22228951
PMCPMC3249911
OpenAlexW2033898136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.