ArticleEuropean journal of applied physiology2012
Determination of the lactate threshold by means of salivary biomarkers: chromogranin A as novel marker of exercise intensity.
Article in European journal of applied physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 49 citations in OpenAlex.
- Changes in saliva composition during different training phases in professional football players.Frontiers in dental medicine · 2026Article
- Influence of iron supplementation on fatigue, mood states and sweating profiles of healthy non-anemic athletes during a training exercise: A double-blind, randomized, placebo-controlled, parallel-group study.Contemporary clinical trials communications · 2023Article
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- Salivary total protein as a biomarker of anaerobic threshold in elderly athletes subjected to an incremental physical test.Biology of sport · 2018Article
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- Salivary alpha amylase not chromogranin A reflects sympathetic activity: exercise responses in elite male wheelchair athletes with or without cervical spinal cord injury.Sports medicine - open · 2017Article
- The Effect of Exercise on Salivary Viscosity.Diagnostics (Basel, Switzerland) · 2016Article
- Cardiac Autonomic and Salivary Responses to a Repeated Training Bout in Elite Swimmers.Sports (Basel, Switzerland) · 2016Article
- Stress Biomarkers, Mood States, and Sleep during a Major Competition: "Success" and "Failure" Athlete's Profile of High-Level Swimmers.Frontiers in physiology · 2016Article
- Biological function and clinical relevance of chromogranin A and derived peptides.Endocrine connections · 2014Article
- Salivary surrogates of plasma nitrite and catecholamines during a 21-week training season in swimmers.PloS one · 2013Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examined intra-individual variations in salivary lactate (sLac), alpha-amylase (sAA) and chromogranin A (sCgA) with reference to the accumulation of blood lactate (bLac) during incremental maximal exercise in swimmers. Samples of blood and saliva were collected simultaneously from 12 male professional athletes during an incremental test that consisted of eight series of 100 m in front crawl with increasing velocity (0.03 m s(-1) each) and 70-s intervals. The concentration of blood and salivary lactate was determined by an electro-enzymatic assay, whereas sAA and CgA were analysed by Western blotting. Inflection points in the concentration of bLAc, sLac, sAA and CgA were found in all subjects. The accumulation of lactate in saliva followed the same pattern observed in blood with a high correlation between the two (r = 0.91). Similar results were observed between the dynamics of sAA (r = 0.81) and sCgA (r = 0.82) in relation to bLac. These findings support the usefulness of saliva for the determination of the lactate threshold and provide the first demonstration of sCgA as a novel marker of exercise intensity in well-trained men.
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