ArticleCell stem cell2012
Tales from the crypt: the expanding role of slow cycling intestinal stem cells.
Article in Cell stem cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing.Pigment cell & melanoma research · 2024Article
- Cellular origins and lineage relationships of the intestinal epithelium.American journal of physiology. Gastrointestinal and liver physiology · 2021Review
- Intestinal Organoids-Current and Future Applications.Veterinary sciences · 2016Review
- Mesenchymal stem cells stimulate intestinal stem cells to repair radiation-induced intestinal injury.Cell death & disease · 2016Article
- Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues.The Journal of physiology · 2016Review
- An organotypic slice model for ex vivo study of neural, immune, and microbial interactions of mouse intestine.American journal of physiology. Gastrointestinal and liver physiology · 2016Article
- Dormant Intestinal Stem Cells Are Regulated by PTEN and Nutritional Status.Cell reports · 2015Article
- Circulating IGF-I and IGFBP3 Levels Control Human Colonic Stem Cell Function and Are Disrupted in Diabetic Enteropathy.Cell stem cell · 2015Article
- Tissue underlying the intestinal epithelium elicits proliferation of intestinal stem cells following cytotoxic damage.Cell and tissue research · 2015Article
- Of mice and women: a comparative tissue biology perspective of breast stem cells and differentiation.Journal of mammary gland biology and neoplasia · 2015Review
- Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling.EMBO reports · 2015Article
- The mammary cellular hierarchy and breast cancer.Cellular and molecular life sciences : CMLS · 2014Review
- Thyroid hormones and their nuclear receptors: new players in intestinal epithelium stem cell biology?Cellular and molecular life sciences : CMLS · 2014Review
- An APC:WNT Counter-Current-Like Mechanism Regulates Cell Division Along the Human Colonic Crypt Axis: A Mechanism That Explains How APC Mutations Induce Proliferative Abnormalities That Drive Colon Cancer Development.Frontiers in oncology · 2013Review
- Intestinal stem cells remain viable after prolonged tissue storage.Cell and tissue research · 2013Article
- Major signaling pathways in intestinal stem cells.Biochimica et biophysica acta · 2013Review
- Alteration of colonic stem cell gene signatures during the regenerative response to injury.Biochimica et biophysica acta · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Similar to other highly self-renewing tissues, the intestinal epithelium contains both slowly and rapidly cycling progenitor/stem cells, though their relationship has been largely unexplored. Two recent reports in Nature (Tian et al., 2011) and Science (Takeda et al., 2011) shed new light on their dynamic interplay.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.