Evidence map›Paper›PMID 22225919›Full record

ArticleBMC women's health2012

Factors associated with treatment of women with osteoporosis or osteopenia from a national survey.

Eric S Meadows, Beth D Mitchell, Susan C Bolge, Joseph A Johnston, Nananda F Col

Open access · goldAbstract read
In one paragraph

Article in BMC women's health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Inhibition of RANKL-Induced Osteoclastogenesis by Novel Mutant RANKL.International journal of molecular sciences · 2021
    Article
  3. Factors affecting willingness to get assessed and treated for osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Article
  4. Cost-Effectiveness of Osteoporosis Screening Using Biomechanical Computed Tomography for Patients With a Previous Abdominal CT.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Osteoporosis treatment disparities: a 6-year aggregate analysis from national survey data.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Article
  11. Alcohol and bone.Wiener medizinische Wochenschrift (1946) · 2014
    Article
  12. Anti-osteoporotic therapy in Denmark--predictors and demographics of poor refill compliance and poor persistence.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Eric S MeadowsGlobal Health Outcomes, Eli Lilly and Company, Indianapolis, IN, USA. es_meadows@yahoo.com
Beth D Mitchell
Susan C Bolge
Joseph A Johnston
Nananda F Col
Eli Lilly (United States) · USGeorgetown University · USOrtho Clinical Diagnostics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth outcomes could be improved if women at high risk for osteoporotic fracture were matched to effective treatment. This study determined the extent to which treatment for osteoporosis/osteopenia corresponded to the presence of specific risk factors for osteoporotic fracture.

methodsThis retrospective analysis of the United States 2007 National Health and Wellness Survey included women age ≥ 40 years who reported having a diagnosis of osteoporosis (69% of 3276) or osteopenia (31% of 3276). Patients were stratified by whether they were or were not taking prescription treatment for osteoporosis/osteopenia. Using 34 patient characteristics as covariates, logistic regression was used to determine factors associated with treatment.

resultsCurrent prescription treatment was reported by 1800 of 3276 (54.9%) women with osteoporosis/osteopenia. The following factors were associated with receiving prescription treatment: patient-reported diagnosis of osteoporosis (versus osteopenia); previous bone mineral density test; ≥ 2 fractures since age 50; older age; lower body mass index; better physical functioning; postmenopausal status; family history of osteoporosis; fewer comorbidities; prescription insurance coverage; higher total prescription count; higher ratio of prescription costs to monthly income; higher income; single status; previous visit to a rheumatologist or gynecologist; and 1 or 2 outpatient visits to healthcare provider (vs. none) in the prior 6 months. Glucocorticoid, tobacco, and daily alcohol use were risk factors for fracture that were not associated with treatment.

conclusionsThere is a mismatch between those women who could benefit from treatment for osteoporosis and those who are actually treated. For example, self-reported use of glucocorticoids, tobacco, and alcohol were not associated with prescription treatment of osteoporosis. Other clinical and socioeconomic factors were associated with treatment (e.g. prescription drug coverage and higher income) or not (e.g. comorbid osteoarthritis and anxiety) and could be opportunities to improve care.

Indexed as

Absorptiometry, PhotonAdultAgedBone Density Conservation AgentsBone Diseases, MetabolicEstrogen Replacement TherapyFemaleHealth SurveysHumansMiddle AgedOsteoporosisOsteoporotic FracturesPractice Patterns, Physicians'Retrospective StudiesRisk FactorsUnited StatesBone Density Conservation Agents

Identifiers

PMID22225919
PMCPMC3295701
OpenAlexW1985021502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.